Akut pankreatitte karbonhidrat antijen 19-9 seviyeleri

Akut pankreatit için birçok etiyolojik faktör bulunmaktadır. Karbonhidrat antijeni 19-9, gastrointestinal malignitelerde, özellikle pankreatikobiliyer kanserde iyi bilinen tümör belirtecidir. Karbonhidrat antijeni 19-9 seviyeleri ayrıca kolestaz gibi iyi huylu hadiselerde de artış gösterir. Bu nedenle akut pankreatit nedeniyle hastanede yatan hastalarda altta yatan etiyolojiler ile karbonhidrat antijeni 19-9 düzeyleri arasındaki ilişkiyi retrospektif olarak araştırmayı amaçladık. Gereç ve Yöntem: Hastanede yatış sırasında ilk 24 saatte karbonhidrat antijeni 19-9 düzeyi bakılan 109 hastanın verilerini retrospektif olarak inceledik. Hastalar akut pankreatit etiyolojisindeki son tanılarına dayanarak biliyer ve non-biliyer olarak iki gruba ayrıldı. Bulgular: Biliyer gruptaki hastaların 63’ünde (%92), non-biliyer gruptaki hastaların 8’inde (%19) karbonhidrat antijeni 19-9 düzeyi 37 U/mL’den yüksek saptandı (p

Carbohydrate antigen 19-9 levels in early acute pancreatitis

There are many etiologic factors responsiblefor acute pancreatitis. Carbohydrate antigen 19-9 is a well-known tumormarker for gastrointestinal malignancies, especially pancreaticobiliarycancer. Carbohydrate antigen 19-9 levels also increase benignevents such as cholestasis. Therefore, the purpose of this study is toretrospectively investigate the relationship between the underlyingetiologies and carbohydrate antigen 19-9 levels in patients who werehospitalized due to acute pancreatitis. Materials and Methods: Weretrospectively analyzed the data of 109 patients who had increasedcarbohydrate antigen 19-9 levels in the first 24 hours during hospitalization.Additionally, we divided the patients into two groups, namelybiliary and nonbiliary, based on their recent diagnoses in the etiologiesof acute pancreatitis. Results: We detected increased carbohydrate antigen19-9 levels (more than 37 U/mL) in 63 (92%) of the patients inthe biliary group, and in 8 (19%) of the patients in the non-biliary group(p

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