Gamze KILIÇARSLAN, Metin ALKAN, Ömer KURTİPEK, Yusuf ÜNAL, Volkan ŞIVGIN, Kürşat DİKMEN, Semin TURHAN, Mustafa ARSLAN

The effect of circadian rhytm in patients undergoing spinal anesthesia

Objectives: The circadian rhythm is the most important of the main rhythms that affect our daily lives and has a significantrole in the efficiency of a lot of drugs used in anesthesia. The aim of this study is to prove whether circadian rhythm has aneffect on spinal anesthesia and, if any, its effect on post-operative analgesic request by retrospectively studying the patientsoperated under spinal anesthesia.Methods: We conducted the study on patients operated on inguinal hernia and anorectal surgery under spinal anesthesia ingeneral surgery room. The patients were divided into two groups according to the time when they were taken into surgery:Between 06.00–12.00 (Group 1) and 12.00–18.00 (Group 2). Time to first analgesic request, time to start walking, time to firsturination, intraoperative and post-operative side effects, intraoperative hemodynamic data, and patient satisfaction were detectedand recorded.Results: The time to first analgesic request in Group 1 was longer than in Group 2, and this difference was statistically significant.The mean heart rate of the groups was found significantly lower in Group 2 than in Group 1 during measurements at the25 and 30 min when compared with their changes overtime. There were no statistically significant differences between thegroups in terms of side effects and the most common side effect was detected to be nausea-vomiting.Conclusion: We found out that the time to first analgesic request after spinal anesthesia was significantly longer in Group 1than in Group 2.

Spinal anestezi uygulanan hastalarda sirkadiyen ritmin etkisi

Amaç: Sirkadiyen ritim günlük yaşamımızda etkisi altında kaldığımız başlıca ritimlerden en önemlisidir ve anestezide kullandığımız birçok ilacın etkinliğinde önemli rol oynamaktadır Bu çalışmanın amacı spinal anestezi altında opere olan hastaları retrospektif olarak inceleyerek sirkadiyen ritmin spinal anestezi uygulanan hastalarda postoperatif analjezi gereksinimi üzerine olan etkisini ortaya koymaktır. Gereç ve Yöntem: Çalışmamız spinal anestezi altında genel cerrahi ameliyathanesinde ingüinal herni ve anorektal cerrahi operasyonu geçiren hastalarda gerçekleştirildi. Hastalar cerrahiye alındıkları saate göre iki gruba ayrıldı: Saat 06.00–12.00 (Grup 1) ve 12.00–18.00 (Grup 2). Postoperatif ilk analjezik gereksinim süreleri, ilk yürüme zamanları, ilk idrar yapma zamanları, intraoperatif hemodinamik veriler, intraoperatif ve postoperatif yan etkiler ve hasta memnuniyetleri belirlenerek kaydedildi. Bulgular: Postoperatif ilk analjezik ihtiyacı zamanı Grup 1’de Grup 2’ye göre daha uzun saptanmış olup, bu fark istatistiksel olarak anlamlı bulundu. Gruplara ait kalp atım hızı ortalamaları, zaman içerisindeki değişimleri açısından karşılaştırıldığında 25. ve 30. dakika ölçümlerinde Grup 2’de Grup 1’e göre anlamlı olarak düşük bulundu. Yan etkilere bakıldığında gruplar arası istatistiksel olarak anlamlı bir fark olmadığı, iki grupta da en sık görülen yan etkinin bulantı-kusma olduğu tespit edildi. Sonuç: Spinal anestezi sonrası ilk analjezi gereksinim zamanının Grup 1’de Grup 2’ye göre anlamlı derecede uzun olduğunu saptadık.

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