COVID-19'lu çocuklarda ABO ve Rh kan gruplarının dağılımı ile klinik seyir arasındaki ilişki

Amaç: Bu çalışma, ABO ve Rh kan gruplarının çocuklarda COVID-19 sıklığını ve semptom gelişimini etkileyip etkilemediğini araştırmayı amaçlamaktadır.Gereç ve Yöntem: Çalışmaya SARS-CoV-2 PCR testi pozitif 337 çocuk ve kontrol grubu olarak 1286 sağlıklı çocuk dahil edildi.Bulgular: Rh (+) çocuklarda hasta oranı, Rh (-) çocuklara göre anlamlı derecede yüksekti (p=0,006). Kan grubu A'nın, COVID-19 vakalarında semptom geliştirme için bir risk faktörü olduğu ve riski artırdığı bulunmuştur. Rh (+) kan grubunun COVID-19 için bağımsız bir risk faktörü olduğu ve COVID-19 vakalarının semptomatik olma oranını artırdığı bulunmuştur.Sonuç: Çalışmamızdan elde edilen veriler, Rh pozitifliğinin çocukları hem COVID-19'a hem de COVID-19 durumunda semptomların gelişimine duyarlı hale getirdiğini ve kan grubu A'nın COVID-19 pozitif çocuklarda semptom geliştirme riskini artırdığını göstermektedir.

Anahtar Kelimeler:

COVID-19, ABO, kan grubu, Rh, çocuk

The relationship between the distribution of ABO and Rh blood groups and the clinical course in children with COVID-19

Aim: This study aims to investigate whether ABO and Rh blood groups affect the prevalence and symptom development of COVID-19 in children.Materials and Methods: The study included 337 children with positive SARS-CoV-2 PCR test and 1286 healthy children as control group.Results: The rate of patients in Rh (+) children was significantly higher than in Rh (-) children (p=0.006). Blood type A has been found to be a risk factor for developing symptoms in COVID-19 cases and increases the risk. It has been found that the Rh (+) blood group is an independent risk factor for COVID-19 and increases the rate of being symptomatic of COVID-19 cases.Conclusion: The findings of our study show that Rh positivity renders children sensitive to the development of clinical symptoms both against COVID-19 and in the case of COVID-19, and blood type A increases the risk of developing symptoms in children with COVID-19.

Keywords:

COVID-19, ABO, Blood group, Rh, Child,

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