FATİH İŞLEYEN, Mehmet Tekin

4824

Alt Solunum Yolu Enfeksiyonu Tanılı İnfant Hastalarda Reaktif Trombositoz

Amaç: Bu çalışmada alt solunum yolu enfeksiyonu (ASYE) tanısı ile yatışı yapılan infant hastalarda başvurudaki reaktif trombositozun yatış süresi ve laboratuvar değerleri ile ilişkisinin incelenmesi amaçlanmıştır.Gereç ve Yöntem: Adıyaman Üniversitesi Eğitim ve Araştırma Hastanesi Süt Çocuğu Kliniği’nde 1 Kasım 2015 ile 31 Ocak 2016 tarihleri arasında ASYE tanısı ile yatışı yapılan 1 ay-24 ay arasındaki hastalarda başvurudaki trombositoz ile yatış süresi, cinsiyet ve laboratuvar bulguları arasındaki ilişki incelendi.Bulgular: Çalışmaya ASYE tanısı alan 219 hasta alındı. Hastaların 104’ü (% 47,5) pnömoni ve 115’i (% 52,5) bronşiolit tanılı idi. Pnömonili hastaların 62’si (% 59,6) erkek ve 42’si (% 40,4) kız iken, bronşiolitli hastaların 74’ü (% 64,3) erkek ve 41’i (% 35,7) kız idi (p=0,489). Pnömonili hastaların 20’sinde (% 19,2), bronşiolitli hastaların ise 10’unda (% 8,7) reaktif trombositoz vardı.  İki grup arasında trombositoz sıklığı açısından anlamlı fark saptandı (p=0,030). Trombositoz saptanan hastalarda yatış süresi 5,7±4,8 gün iken, trombositoz saptanmayan hastalarda 4,3±2,8 gün idi (p=0,023). Reaktif trombositoz saptanan hastalarda yatış süresi trombositoz saptanmayan hastalara göre anlamlı düzeyde uzun idi. Sonuç: Çalışmamızda pnömonili hastalardaki reaktif trombositoz görülme sıklığının bronşiolitli hastalara kıyasla daha yüksek olduğu gözlendi. Reaktif trombositoz gelişen ASYE tanılı infant hastalarda yatış süresinin, trombositoz saptanmayan hastalara göre daha uzun olduğu saptandı.
Anahtar Kelimeler:

Alt Solunum Yolu Enfeksiyonu, Reaktif Trombositoz, Süt Çocuğu

Reactive Thrombocytosis in Infant Patients Diagnosed with Lower Respiratory

Aim: The aim of this study was to investigate the relationship between reactive thrombocytosis in admission to hospital and hospitalization time and laboratory values in hospitalized infant patients with lower respiratory tract infection (LRTI) diagnosisMaterial and methods: The relationship between thrombocytosis in admission and duration of hospitalization, gender and laboratory findings was evaluated in patients between 1-24 months of age who were diagnosed with LTRI between 1 November 2015 and 31 January 2016 in Adiyaman University Training and Research Hospital Infant Clinic.Results: A total of 219 patients diagnosed with LRTI were included in the study. One hundred and four (47.5%) of the patients were diagnosed with pneumonia and 115 (52.5%) were diagnosed with bronchiolitis. Sixty two of the patients with pneumonia (59.6%) were male and 42 (40.4%) were female, 74 (64.3%) of the patients with bronchiolitis were male and 41 (35.7%) were female (p = 0,489). Reactive thrombocytosis was present in 20 (19.2%) patients with pneumonia and 10 (8.7%) patients with bronchiolitis. There was a significant difference in the frequency of thrombocytosis between the two groups (p = 0.030). The duration of hospitalization was 5.7 ± 4.8 days in patients with thrombocytosis, and 4.3 ± 2.8 days in patients without thrombocytosis (p = 0.023). The duration of hospitalization in patients with reactive thrombocytosis was significantly longer than in those without thrombocytosis. Conclusion: In our study, it was observed that the incidence of reactive thrombocytosis in patients with pneumonia was higher than in patients with bronchiolitis. The duration of hospitalization in infants with ASE diagnosed with reactive thrombocytosis was longer than in patients without thrombocytosis.
Keywords:

Lower Respiratory Tract Infection, Reactive Thrombocytosis, Infant,

PDF

___

  • 1. Matsubara K, Fukaya T, Nigami H, Harigaya H, Hirata T, Nozaki H, Baba K. Age-dependent changes in the incidence and etiology of childhood thrombocytosis. Acta Haematol 2004;111:132-137.
  • 2. Dame C, Sutor AH. Primary and secondary thrombocytosis in childhood. Br J Haematol 2005;129:165-177.
  • 3. Mantadakis E, Tsalkidis A, Chatzimichael A. Thrombocytosis in childhood. Indian Pediatr 2008;45:669-677.
  • 4. Schafer AI. Thrombocytosis. N Engl J Med 2004;350:1211-1219.
  • 5. Sutor AH. Thrombocytosis in childhood. Semin Thromb Hemost 1995;21:330-339.
  • 6. Ishiguro A, Suzuki Y, Mito M, Shimbo T, Matsubara K, Kato T, Miyazaki H. Elevation of serum thrombopoietin precedes thrombocytosis in acute infections. Br J Haematol 2002;116:612-618.
  • 7. Shebl SS, el-Sharkawy HM, el-Fadaly NH. Haemostatic disorders in nonsplenectomized and splenectomized thalassaemic children. East Mediterr Health J 1999;5:1171-1177.
  • 8. Sutor AH. Screening children with thrombosis for thrombophilic proteins. Cui bono? J Thromb Haemost 2003;1:886-888.
  • 9. Borgna Pignatti C, Carnelli V, Caruso V, Dore F, De Mattia D, Di Palma A, Di Gregorio F, Romeo MA, Longhi R, Mangiagli A, Melevendi C, Pizzarelli G, Musumeci S. Thromboembolic events in beta thalassemia major: an Italian multicenter study. Acta Haematol 1998;99:76-79.
  • 10. Wohl MEB. Bronchiolit. In: Chernick V, Boat TF, eds. Kendig’s Disorders of the Respiratory Tract in Children, 7th edition, Philadelphia: W.B Saunders, 2006:423-32.
  • 11. Fitzgerald DA, Kilham HA. Bronchiolitis: assessment and evidence-based medicine. Med J Aust 2004;180:399-404.
  • 12. Türk Toraks Derneği Akut Bronşiolit Tanı ve Tedavi Uzlaşı Raporu. Turk Thorac J 2009;10:1-7.
  • 13. Barson WJ. Epidemiology, pathogenesis, and etiology of pneumonia in children. Version 16.3 http://www.uptodate.com (accessed June, 2008), http//www.utdol.com/online.
  • 14. Ostapchuk M, Roberts D, Haddy R. Community-Acquired Pneumonia in Infants and Children. Am Fam Physician 2004;70:899-908.
  • 15. Stein RT, Marostica PJC, Community-acquired pneumonia. Paediatr Respir Rev 2006;7:136-7.
  • 16. Wang JL, Huang LT, Wu KH, Lin HW, Ho MY, Liu HE. Associations of reactive thrombocytosis with clinical characteristics in pediatric diseases. Pediatr Neonatol 2011;52:261-6.
  • 17. Chen HL, Chiou SS, Sheen JM. Thrombocytosis in hospitalized children. Pediatr Infect Dis 1992;11:456-460.
  • 18. Yohannan MD, Higgy KE, Al-Mashhadani SA, Santhos-Kumar CR. Trombocytosis. Clin Pediatr 1994;33: 340-343.
  • 19. Garoufi A, Voutsioti K, Tsapra H, Kaspathios T, Zeis PM. Reactive thrombocytosis in children with upper urinary tract infection. Acta Pediatr Taiwan 1999; 309-313.
  • 20. Vlacha V, Feketea G. Thrombocytosis in pediatric patients is associated with severe lower respiratory tract inflammation. Arch Med Res 2006;37(6):755-9.21. Wolach B, Morag H, Drucker M, Sadan N. Trombocytosis after pneumonia with empyema and other bacterial infection in children. Pediatr İnfect Dis J 1990;9:718-721.
  • 22. Vora AJ, Lilleyman JS .Sekondary thrombocytosis. Arch Dis Child 1993;68:88-90.
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi-Cover
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2015
  • Yayıncı: ADIYAMAN ÜNİVERSİTESİ
Arşiv
Sayıdaki Diğer Makaleler

Prostat Volüm Ölçümünde Transabdominal Ultrasonografi ile Kontrastlı Bilgisayarlı Tomografi Sonuçlarının Karşılaştırılması

Mehmet ŞİRİK, Şükrü ŞAHİN, İbrahim İNAN

Alt Solunum Yolu Enfeksiyonu Tanılı İnfant Hastalarda Reaktif Trombositoz

FATİH İŞLEYEN, Mehmet Tekin

SUBLİNGUAL RANULA: OLGU SUNUMU

Günay YAPICI YAVUZ, Muhammet Selim YAVUZ, Mahmut KOPARAL

Kolon Volvuluslarının Tedavisinde Mortaliteyi Etkileyen Nedenler

Bayram ÇOLAK, Burcu YORMAZ, İlhan ECE, Serdar YORMAZ, Hüseyin YILMAZ, Mustafa ŞAHİN

Farmakomekanik Rotasyonel Trombektomi Sirasinda Hastada Kirilan Guide Parçasinin Subclaviyan Yolla Çikartilmasi

Cengiz Güven

Korneal Yabancı Cisim Hastalarının Uygulamaları ve Güvenlik Gözlükleri Kullanma Oranları

Ali ŞİMŞEK, Tanju TEKER, Eyyüp Murat KARAKURT, Alper YALCIN