Fevziye KABUKÇUOĞLU, Yavuz KABUKÇUOĞLU, Metin KÜÇÜKKAYA, Ünal KUZGUN, Semiha KESKİN

Dev hücreli kemik tümörünün ince iğne aspirasyon sitolojisi

Amaç: İnce iğne aspirasyonu (İİA) yöntemi ile, dev hücreli kemik tümörünün sitolojik bulgularının incelenmesi ve dev hücre içerebilen diğer benign ve malign kemik lezyonları ile ayırıcı tanı özelliklerinin belirlenmesi. Çalışma planı: Klinik ve radyolojik olarak dev hücreli kemik tümörü düşünülen yedi olguda İİA uygulandı. Preparatlar Papanicolaou yöntemi ile boyandı. Sitolojik bulgular daha sonra operasyon materyallerinin histopatolojik özellikleri ile karşılaştırıldı. Sonuçlar: Beş olguda sitolojik inceleme için yeterli materyal elde edildi. İzlenen çok sayıda multinükleer dev hücreler ve yer yer bunlara bitişik stromal hücre kümeleri dev hücreli kemik tümörü ile uyumlu bulundu. İki olgu, yaygın kan elemanları ve düşük sellülerite nedeniyle değerlendirilemedi. Çıkarımlar: Klinik ve radyolojik bulgular ile birlikte değerlendirildiğinde, İİA yönteminin dev hücreli kemik tümörünün preoperatif tanısında yararlı olacağı sonucuna varıldı.

Anahtar Kelimeler:

Sitolojik teknikler, Dev hücreli kemik tümörü, Kemik neoplazmları, Dev hücreli tümörler, Biyopsi, iğne, Sitolojik tanı

Fine needle aspiration cytology of giant cell tumors

Objectives: To evaluate cytologic findings of giant cell tumors using fine needle aspiration (FNA) and to determine their differential features from other benign and malignant lesions containing giant cells. Methods: Fine needle aspiration was performed in seven lesions with a clinical and radiological diagnosis of giant cell tumor. The slides were stained using the Papanicolaou method. The results were compared with those of histopathology of subsequent open biopsies. Results: Sufficient material was obtained in five cases. Numerous multinucleate giant cells adjacent to stromal cell clusters were consistent with giant cell tumor. In two cases, evaluation was not possible due to hemorrhagic material with low cellularity. Conclusion: Fine needle aspiration may play a valuable role in the diagnosis of giant cell tumors when used in conjunction with clinical and radiographic findings.

Keywords:

Cytological Techniques, Giant Cell Tumor of Bone, Bone Neoplasms, Giant Cell Tumors, Biopsy, Needle, Cytodiagnosis,

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