Medulloblastoma ve Güncel Tedavi Yaklaşımları

Medulloblastom çocukluk çağının ikinci en sık görülen ve en malign beyin tümörüdür. Yetişkinlerde ise oldukça nadir rastlanır. Medulloblastom tanılı hastalar tedavi öncesi standart risk ve yüksek riskli olmak üzere iki gruba ayrılır. Cerrahi rezeksiyonu takiben kraniospinal radyoterapi (KSRT) tedavinin temelini oluşturur. Günümüzde tedaviye kemoterapinin eklenmesi sağkalımın artmasına katkıda bulunmuştur. Ayrıca kemoterapinin eklenmesi ile total radyoterapi dozu da düşürülmüştür. Tedavide yeni kemoterapik ajanların geliştirilmesi ve yeni radyoterapi teknikleri hastaların uyumunu arttırmıştır.

Current Treatment of Medulloblastoma

Medulloblastoma is the second most common and most malignant brain tumor in children. But in adults medulloblastomas occur rarely. The patients with medulloblastoma are stratified two groups before treatment: avarage risk and high risk. Surgical resection followed by craniospinal irradiation (CSI) has been the mainstay of medulloblastoma therapy. In recent years, chemotherapy has been introduced to reduce the total dose of radiation and increase the survival rate. The new radiotherapy techniques and chemotherapy agents increase compliance to treatment.

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Acta Oncologica Turcica-Cover
  • ISSN: 0304-596X
  • Başlangıç: 2015
  • Yayıncı: Dr. Abdurrahman Yurtaslan Ankara Onkoloji EAH
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