Ortodontik tedavide karşılaşılan allerjik reaksiyonlar

Allerji, normalde zararsız olan maddelere karşı oluşan uygunsuz ve zararlı bir cevap olarak tanımlanabilir. Diş hekimliğinin bütün alanlarında olduğu gibi ortodontide de allerjik reaksiyonlarla sıklıkla karşılaşılmaktadır. Ortodontik materyallere karşı istenmeyen hasta reaksiyonları hem irritan hem de hipersensitivite reaksiyonları şeklinde görülebilmektedir. İrritan orijinli reaksiyonlar yumuşak dokular ve ortodontik aparey kısımları arasındaki direkt sürtünmeden kaynaklanmaktadır. Hipersensitivite reaksiyonları ise bazı materyallerin antijenitesine bağlıdır ve istenmeyen hasta cevabıyla sonuçlanmaktadır. Hipersensitivite reaksiyonları genelde yüz ve boyunda allerjik kontakt dermatit olarak kendini gösterse de, mukozal ve gingival reaksiyonlar, potansiyel genel dermal ve sistemik reaksiyonlar da nadir olarak görülebilmektedir. Ortodontik tedavide en sık karşılaşılan allerjik reaksiyonlar lateks, metal ve akrilik rezin kaynaklıdır. Bu materyallerin dışında braketlerin yapıştırılmasında kullanılan bonding ajanlarına, ekstraoral apareylere, dezenfektanlarave antimikrobial ajanlarakarşı allerjik reaksiyonlar gelişebilmektedir. Ekstraoral apareyler nedeniyle oluşan reaksiyonlar apareylerin metalik, elastik kısımlarına veya doku ile temasta olan aparey parçalarına bağlı olarak gelişebilmektedir. Ortodontistlerin uygulanan tedavi sırasında allerjik reaksiyonlar açısından dikkatli olması, hastanın genel sağlığının korunması açısından önem taşımaktadır. Bu derlemenin amacı, ortodontik tedavi sırasında sıklıkla karşılaşılan allerjik reaksiyonları incelemek ve hekimin alabileceği önlemleri tartışmaktır.

Allergic reactions seen in orthodontic treatment

Allergy can be defined as inappropriate and harmful response to harmless and ordinary materials. Allergic reactions, like in other fields of dentistry, can also be seen in the field of orthodontics. The reactions that occur against orthodontic materials can be seen as irritant or hypersensitivity reactions. The main reason of the irritant reactions is friction between soft tissues and orthodontic appliances. However, the reason of the hypersensitivity reactions is usually the antigenicity of the materials. Hypersensitivity reactions are usually seen as allergic contact dermatitis on face and neck; the occurrence of mucosal-gingival reactions and dermal and systemic reactions are rare. Latex, metal and acrylic resins are the most common allergens in orthodontics. Apart from these materials, allergic reactions can occur against bonding materials, extraoral appliances, disinfectants and antimicrobial agents. The reactions that occur against extraoral appliances usually result from metallic and elastic parts of the appliances or the appliance parts that are in contact with skin. Orthodontists should be aware of the allergic reactions to protect their patients’ health. The aim of this review was to evaluate the allergic reactions seen in orthodontic patients and discuss the cautions that orthodontists can take.

___

  • Dickson G. Contact dermatitis and cervical head-gear. Br Dent J 1983;155:112.
  • Brooks MH, Curzon MG. 'Orthodontic headgear related to allergic contact dermatitis'. Br Dent J 1991;171:124.
  • Lowey MN. Allergic contact dermatitis associated with the use of an Interlandi headgear in a patient with a history of atopy. Br Dent J 1993;175:67-72.
  • Jacobsen N, Hensten-Pettersen A. Changes in occupational health problems and adverse patient reactions in orthodontics from 1987 to 2000. Eur J Orthod 2003;25:591-8.
  • Kanerva L, Lahtinen A, Toikkanen J, Forss H, Estlander T, Susitaival P, et al. Increase in occupational skin diseases of dental personnel. Contact Dermatitis 1999;40:104-8.
  • Jacobsen N, Hensten-Pettersen A. Occupational health problems and adverse patient reactions in orthodontics. Eur J Orthod 1989;11:254-64.
  • Paredes V, Paredes C. Allergic contact dermatitis associated with the use of facemask on a patient with a history of atopy. J Dent Child (Chic) 2010;77:177-9.
  • Rai R, Dinakar D, Kurian SS, Bindoo YA. Investigation of contact allergy to dental materials by patch testing. Indian Dermatol Online J 2014;5:282-6.
  • Rubel DM, Watchorn RB. Allergic contact dermatitis in dentistry. Australas J Dermatol 2000;41:63-9.
  • Goldberg M. In vitro and in vivo studies on the toxicity of dental resin components: a review. Clin Oral Invest 2008;12:1-8.
  • Lunder T, Rogl-Butina M. Chronic urticaria from an acrylic dental prosthesis. Contact Dermatitis 2000;43:232-3.
  • Ruiz-Genao DP, Moreno de Vega MJ, Sánchez Pérez J, GarcíaDíez A. Labial edema due to an acrylic dental prosthesis. Contact Dermatitis 2003;48:273-4.
  • Giunta J, Zablotsky N. Allergic stomatitis caused by self-polymerizing resin. Oral Surg Oral Med Oral Path 1976;41:631-7.
  • McCabe JF, Basker RM. Tissue sensitivity to acrylic resin. A method of measuring the residual monomer content and its clinical application. Br Dent J 1976;140:347-50.
  • Yilmaz H, Aydin C, Caglar A, Yasar A. The effect of glass fiber reinforcement on the residual monomer content of two denture base resins. Quintessence Int 2003;34:148-53.
  • Devlin H, Watts DC. Acrylic 'allergy'? Br Dent J 1984;157:272-5.
  • Goncalves TS, Morganti MA, Campos LC, Rizzatto SM, Menezes LM. Allergy to auto-polymerized acrylic resin in an orthodontic patient. Am J Orthod Dentofacial Orthop 2006;129:431-5.
  • Rahilly G, Price N. Current products and practice nickel allergy and orthodontics. J Orthod 2003;30:171-4.
  • Noble J, Ahing SI, Karaiskos NE, Wiltshire WA. Nickel allergy and orthodontics, a review and report of two cases. Br Dent J 2008;204:297-300.
  • Chakravarthi S, Padmanabhan S, Chitharanjan AB. Allergy and orthodontics. J Orthod Sci 2012;1:83-7.
  • Kolokitha OE, Kaklamanos EG, Papadopoulos MA. Prevalence of nickel hypersensitivity in orthodontic patients: a meta-analysis. Am J Orthod Dentofacial Orthop 2008;134:722.e1-12.
  • Staerkjaer L, Menné T. Nickel allergy and orthodontic treatment. Eur J Orthod 1990;12:284-9.
  • Bass JK, Fine H, Cisneros GJ. Nickel sensitivity in the orthodontic patient. Am J Orthod Dentofac Orthop 1993;103:280-5.
  • Kuhta M, Pavlin D, Slaj M, Varga S, Lapter-Varga M, Slaj M. Type of archwire and level of acidity: effects on the release of metal ions from orthodontic appliances. Angle Orthod 2009;79:102-10.
  • Kalimo K, Mattila L, Kautiainen H. Nickel allergy and orthodontic treatment. J Eur Acad Dermatol Venereol 2004;18:543-5.
  • Geukens S, Goossens A. Occupational contact allergy to (meth)acrylates. Contact Dermatitis 2001;44:153-9.
  • Setcos JC, Babaei-Mahani A, Silvio LD, Mjör IA, Wilson NH. The safety of nickel containing dental alloys. Dent Mater 2006;22:1163-8.
  • Barrett RD, Bishara SE, Quinn JK. Biodegradation of orthodontic appliances. Part I. Biodegradation of nickel and chromium in vitro. Am J Orthod Dentofacial Orthop 1993;103:8-14.
  • Genelhu MC, Marigo M, Alves-Oliveira LF, Malaquias LC, Gomez RS. Characterization of nickel-induced allergic contact stomatitis associated with fixed orthodontic appliances. Am J Orthod Dentofacial Orthop 2005;128:378-81.
  • Pazzini CA, Pereira LJ, Carlos RG, de Melo GE, Zampini MA, Marques LS. Nickel: periodontal status and blood parameters in allergic orthodontic patients. Am J Orthod Dentofacial Orthop 2011;139:55-9.
  • Pazzini CA, Júnior GO, Marques LS, Pereira CV, Pereira LJ. Prevalence of nickel allergy and longitudinal evaluation of periodontal abnormalities in orthodontic allergic patients. Angle Orthod 2009;79:922-7.
  • Gursoy UK, Sokucu O, Uitto VJ, Aydin A, Demirer S, Toker H, et al. The role of nickel accumulation and epithelial cell proliferation in orthodontic treatment-induced gingival overgrowth. Eur J Orthod 2007;29:555-8.
  • Janson GR, Dainesi EA, Consolaro A, Woodside DG, de Freitas MR. Nickel hypersensitivity reaction before, during, and after orthodontic therapy. Am J Orthod Dentofacial Orthop 1998;113:655-60.
  • Bour H, Nicolas JF, Garrigue JL, Demidem A, Schmitt D. Establishment of nickel-specific T cell lines from patients with allergic contact dermatitis: comparison of different protocols. Clin Immunol Immunopathol 1994;73:142-5.
  • Romageura C, Grimalt F, Vilaplana J. Contact dermatitis from nickel: an investigation of its sources. Contact Dermatitis 1988;19:52-7.
  • Thyssen JP, Linneberg A, Menné T, Johansen JD. The epidemiology of contact allergy in the general population--prevalence and main findings. Contact Dermatitis 2007;57:287-99.
  • Menezes LM, Campos LC, Quintão CC, Bolognese AM. Hypersensitivity to metals in orthodontics. Am J Orthod Dentofac Orthop 2004;126:58-64.
  • Lu LK, Warshaw EM, Dunnick CA. Prevention of nickel allergy: the case for regulation? Dermatol Clin 2009;27:155-61.
  • Kolokitha OE, Chatzistavrou E. A severe reaction to ni-containing orthodontic appliances. Angle Orthod 2009;79:186-92.
  • Kocadereli L, Atac A, Kale S, Ozer D. Salivary nickel and chromium in patients with fixed orthodontic appliances. Angle Orthod 2000;70:431-4.
  • Shah M, Lewis FM, Gawkrodger DJ. Delayed and immediate orofacial reactions following contact with rubber gloves during dental treatment. Br Dent J 1996;181:137-9.
  • Yunginger JW, Jones RT, Fransway AF, Kelso JM, Warner MA, Hunt LW. Extractable latex allergens and proteins in disposable medical gloves and other rubber products. J Allergy Clin Immunol 1994;93:836-42.
  • Rubel DM, Watchorn RB. Allergic contact dermatitis in dentistry. Australas J Dermatol 2000;41:63-9.
  • Heese A, van Hintzenstern J, Peters KP, Koch HU, Hornstein OP. Allergic and irritant reactions to rubber gloves in medical health services. Spectrum, diagnostic approach, and therapy. J Am Acad Dermatol 1991;25:831-9.
  • del Savio B, Sheretz EF. Is allergic contact dermatitis being overlooked? Arch Fam Med 1994;3:537-43.
  • Field EA, Fay MF. Issues of latex safety in dentistry. Br Dent J 1995;179:247-53.
  • Hain MA, Longman LP, Field EA, Harrison JE. Natural rubber latex allergy: implications for the orthodontis. J Orthod 2007;34:6-11.
  • Krouse JH. Allergy and immunology: an otolaryngic approach, 1st edn. Philadelphia: Lippincott Williams & Wilkins; 2002.
  • Natrass C, Ireland AJ, Lovell CR. Latex allergy in an orthognathic patient and implications for clinical management. Br J Oral Maxillofac Surg 1999;37:11-3.
  • Cronin E. Contact dermatitis, 1 st edn. Edinburgh: Churchill Livingstone; 1980
  • Leite LP, Bell RA. Adverse hypersensitivity reactions in orthodontics. Sem Orthod 2004;10:240-3.
  • Nichols KM, Cook-Bolden FE. Allergic skin disease: major highlights and recent advances. Med Clin North Am 2009;93:1211-24.
  • Lieberman P, Anderson JA. Allergic diseases diagnosis and treatment, 2nd edn. Totowa, NJ: Humana Press; 2000.
  • Coombs RR, Gell PG. Clinical aspects of immunology, 1st edn. Oxford, England: Blackwell; 1963.
  • Smith HE, Frew AJ. Allergy: your questions answered, 1st edn. Edinburgh: Churchill Livingstone; 2003.
  • Arshad SH. Allergy an illustrated colour text, London: Churchill Livingstone; 2002.
Acta Odontologica Turcica-Cover
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1984
  • Yayıncı: Gazi Üniversitesi Diş Hekimliği Fakültesi Dergisi
Sayıdaki Diğer Makaleler

Sialolit: 3 olgunun klinik, radyografik ve ultrasonografik bulguları ile birlikte değerlendirilmesi

Melih Özdede, Nur Hacıosmanoğlu, Elif Kaya, Halil Özer, Emre Akın, Anıl Seçkin, Sharif Rzayev

Ortodontik tedavide karşılaşılan allerjik reaksiyonlar

Hande Görücü Coşkuner, İlken Kocadereli

Yıkama süresinin elastomerik ölçü materyallerinin ıslanabilirliği üzerine etkisi: in vitro çalışma

Özlem Acar, Selim Erkut

Diş hekimliğinde kemik yaşı tayininde kullanılan yöntemler: derleme

Yelda Kasımoğlu, Elif Bahar Tuna-İnce

Eagle sendromu: olgu bildirimi

Nilüfer Ersan, Mehmet İlgüy, Dilhan İlgüy

İnternal matriks ile birlikte kullanılan MTA’nın ortograd ve retrograd uygulanmasının farklı apikal açıklığa sahip dişler üzerindeki güçlendirme etkisinin değerlendirilmesi

Emre Bayram, Hüda Melike Bayram, Hakan Eren

Farklı polimerizasyon protokolleri ve yüzey uygulama metodlarının iki farklı fissür örtücünün makaslama bağlanma dayanım kuvveti üzerine etkisi

Sezin Özer, Nihan Gönülol, Emine Şen Tunç, Tuba Ay

Deneyimin kompozit rezinlerin renk seçimi üzerine etkisinin bir spektrofotometre kullanılarak değerlendirilmesi

Duygu Recen, Banu Önal, Lezize Şebnem Türkün

Protetik diş hekimliğinde 3-boyutlu implant planlama ve cerrahi kılavuzlar

Abdullah Oğuz Hamiş, Oğuz Ozan, Serhat Ramoğlu

İnternal matriks ile birlikte kullanılan MTA'nın ortograd ve retrograd uygulanmasının farklı apikal açıklığa sahip dişler üzerindeki güçlendirme etkisinin değerlendirilmesi

Hüda Melike BAYRAM, Hakan EREN, Emre BAYRAM