Dilek MENZİLETOĞLU, Alparslan ESEN, Bozkurt Kubilay IŞIK

Effect of platelet-rich fibrin in reducing postoperative complications after impacted third molar surgery: a prospective, randomized controlled clinical trial

AMAÇ: Bu çalışmanın birincil amacı, mandibular gömülü yirmi yaş dişi cerrahisi sonrası, antibiyotik kullanılmaksızın trombositten zengin fibrinin postoperatif ağrı, şişlik ve trismus üzerine etkilerini incelemektir. Ayrıca, diğer bir amaç da hastaların postoperatif dönemdeki yaşam kalitelerini değerlendirmektir.GEREÇ VE YÖNTEM: Bu çalışmaya kemik retansiyonlu, üzeri tamamen mukoza ile kapalı, meziyo-angular pozisyonda gömülü dişlere sahip toplam 40 hasta dahil edildi. Hastalar iki gruba ayrıldı. Birinci gruptaki hastaların çekim soketine trombositten zengin fibrin yerleştirildi; ikinci gruba sadece geleneksel cerrahi uygulandı (soket boş bırakıldı). Bütün cerrahi işlemler lokal anestezi altında aynı cerrah tarafından yapıldı. Cerrahi sonrası hastalara antibiyotik reçete edilmedi. Yedi günlük takip periyodunda hastaların ağrı, şişlik, trismus ve yaşam kalitesi kayıtları değerlendirildi.BULGULAR: Hastaların yaş ortalaması birinci grupta 23.3 (±3.9) ve ikinci grupta 23.3 (±4.6) olarak bulundu. İstatistiksel analizler iki grup arasında postoperatif ağrı, şişlik, ağız açıklığı ve yaşam kalitesi skorları açısından fark olmadığını gösterdi (p>0.05).SONUÇ: Gömülü yirmi yaş dişi cerrahisinde trombositten zengin fibrin kullanımının postoperatif ağrı, şişlik, trismus ve yaşam kalitesi üzerine önemli bir etkisi olmadığı sonucuna varıldı.

Trombositten zengin fibrinin gömülü yirmi yaş dişi cerrahisi sonrası postoperatif komplikasyonların azaltılmasına etkisi: prospektif, randomize kontrollü klinik araştırma

OBJECTIVE: The first aim of this study was to evaluate the effect of platelet-rich fibrin (PRF) on pain, swelling, and trismus after mandibular impacted third molar surgery without the use of postoperative antibiotics. A second aim was to evaluate the patients' quality of life (QOL) during the postoperative period.MATERIALS AND METHOD: Forty patients, who had bony impacted, mesio-angular mandibular third molars that were fully covered with mucosa, were selected. Patients were divided into two groups: PRF was placed in the socket in the first group and, traditional surgery was performed in the second group (the socket was left empty). The same surgeon performed all surgeries under local anesthesia. No antibiotics were prescribed after surgery. The outcome variables were pain, swelling, trismus, and QOL over a follow-up period of seven days.Results: The mean age of the patients was 23.3 (±3.9) years in the first group, and 23.3 (±4.6) years in the second group. Statistical analyses of the postoperative results showed that there were no significant differences between the groups with regard to pain, swelling, trismus, and QOL scores (p>0.05).CONCLUSION: The present study showed that PRF use had no significant effect on the postoperative pain, swelling, trismus, and QOL after impacted third molar surgery.

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