Strain Imaging by Speckle Tracking for the Assessment of Diastolic Dysfunction in Beta-Thalassemia Major Patients

Objectives: Strain imaging is a novel promising echocardiographic technique and strain imaging by speckle tracking has been reported recently in a few studies as a promising tool to detect early changes of myocardial deformation that could be related to myocardial iron over load in patients with β-thalassemia major. In this study, we investigated strain images in comparison with the cardiac T2* magnetic resonance imaging results. Materials and Methods: A total of 45 patients from a single institution’s pediatric and adult hematology centers were evaluated with strain echocardiography and T2* magnetic resonance imaging at concomitant out-patient visits. We grouped patients according to cardiac T2* magnetic resonance imaging results:

Kaynakça

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[10]Gorcsan J, 3rd, Tanaka H. Echocardiographic assessment of myocardial strain. Journal of the American College of Cardiology 2011; 58(14): 1401-13.

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[15]Garceau P, Nguyen ET, Carasso S, et al. Quantification of myocardial iron deposition by two-dimensional speckle tracking in patients with beta-thalassaemia major and Blackfan-Diamond anaemia. Heart 2011; 97(5): 388-93.

[16]Karamanou AG, Hamodraka ES, Vrakas SC, et al. Assessment of left ventricular and atrial diastolic function using two-dimensional (2D) strain imaging in patients with beta-thalassemia major. Eur J Haematol 2014; 92(1): 59-65.

[17]Parsaee M, Akiash N, Azarkeivan A, et al. The correlation between cardiac magnetic resonance T2* and left ventricular global longitudinal strain in people with beta-thalassemia. Echocardiography 2018; 35(4): 438-44.

[18]Pizzino F, Meloni A, Terrizzi A, et al. Detection of myocardial iron overload by two-dimensional speckle tracking in patients with beta-thalassaemia major: a combined echocardiographic and T2* segmental CMR study. The International Journal of Cardiovascular Imaging 2018; 34(2): 263-71.

Kaynak Göster

  • ISSN: 2147-9488
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012

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