Süper Bakteriler İçin Antibiyotik Arayışı

Metisilin-dirençli Staphylococcus aureus Methicillin resistant Staphylococcus aureus- MRSA , Vankomisin dirençli Staphylococcus aureus Methicillin resistant Staphylococcus aureus - VRSA , Vankomisin dirençli Enterococcus Vancomycin resistant Enterococcus - VRE , Streptococcus pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Clostridium difficile, çoklu ilaç dirençli Mycobacterium tuberculosis gibi bazı bakteriler ilaçların etkilerinden kurtulma yolları geliştirmişlerdir. Direnç mekanizmaları araştırılmakla birlikte bu dirençli mikroorganizmalar sağlık çalışanları için halen sorunlar oluşturmaktadır. Bazı yeni antibakteriyel silahlar bu tip bakterilerle başa çıkmak için kullanılabilir. Bu yazıda günümüzde karşılaşılan dirençli bakterilere karşı geliştirilen ve tedavide başarıyla kullanılan yeni antibiyotiklerin gözden geçirilmesi amaçlanmıştır

Novel Antibiotic Search For Superbugs

Some of the bacteria like Methicillin-resistant Staphylococcus aureus MRSA , Vancomycin-resistant Staphylococcus aureus VRSA , Vancomycinresistant Enterococcus VRE , Streptococcus pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Clostridium difficile, multidrug resistant Mycobacterium tuberculosis have developed many different ways to escape from the drugs’ effects. The resistance mechanisms are being investigated, but meanwhile those resistant bacteria continue to be a problem for patients and health care workers. There are some new antibacterial weapons to cope with these bacteria. The aim of this manuscript is to review current resistant bacteria and the new antibiotics developed to manage them successfully.

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