Pulmoner Sarkoidozlu Bir Hastanın F-18 FDG PET/BT Görüntülemesi

Son yıllarda, PET/BT malignite düşünülen pulmoner ve mediastinal lezyonların tanısında sıklıkla kullanılmaktadır. Ancak artmış F-18 FDG tutulumu gösteren, SUVmaks değerinin 2.5’ten fazla olduğu aspergilloz, tuberküloz, Wegener granulomatozu, ve sarkoidoz gibi inflamatuar ve granulomatoz hastalıklar yanlış pozitif sonuçlara neden olabilmektedir. Bu çalışmada malignite şüphesi ile araştırılan pulmoner sarkoidozlu bir hastanın ilginç F-18 FDG PET/BT görüntüleme bulguları sunulmuştur

F-18 Fdg Pet/ct Imaging In a Patient With Pulmonary Sarcoidosis

Recently, PET/CT has been used increasingly in the detection of pulmoner and mediastinal lesions. However, inflamatory and granulomatous diseases that show increased F-18 FDG uptake and have SUVmax values more than 2.5, such as aspergillosis, tuberculosis, Wegener granulomatosis and sarcoidosis may cause false positive results. In this case, F-18 FDG PET/BT imaging findings were presented in a patient with pulmonary sarcoidosis who was investigated for primarily suspected malignancy

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Cook GJ, Fogelman I, Maisey MN. Normal physiological and benign pathological variants of 18-fluoro-2-deoxyglucose positron-emission tomography scanning: potential for error in interpretation. Semin Nucl Med. 1996;26(4):308-14.

Brudin LH, Valind SO, Rhodes CG, Pantin CF, Sweatman M, Jones T, et al. Fluorine-18 deoxyglucose uptake in sarcoidosis measured with positron emission tomography. Eur J Nucl Med. 1994;21(4):297-305.

Lewis PJ, Salama A. Uptake of fluorine-18-fluorodeoxyglucose in sarcoidosis. J Nucl Med. 1994;35(10):1647-9.

Gotway MB, Storto ML, Golden JA, Reddy GP, Webb WR. Incidental detection of thoracic sarcoidosis on whole-body 18fluorine-2- fluoro-2-deoxy- D-glucose positron emission tomography. J Thorac Imaging. 2000;15(3):201-4.

Braun JJ, Kessler R, Constantinesco A, Imperiale A. (18)F-FDG PET/CT in sarcoidosis management: review and report of 20 cases. Eur J Nucl Med Mol Imaging, 2008 35(8):1537–1543.

Arfi J, Kerrou K, Traore S, Huchet V, Bolly A, Antoine M, et al. F-18 FDG PET/CT findings in pulmonary necrotizing sarcoid granulomatosis. Clin Nucl Med. 2010 Sep;35(9):697-700.

Basu S, Saboury B, Werner T, Alavi A. Clinical Utility of FDG-PET and PET/CT in Non-malignant Thoracic Disorders. Mol Imaging Biol. 2010 Dec 16.

Acıbadem Üniversitesi Sağlık Bilimleri Dergisi-Cover
  • ISSN: 1309-470X
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2010
  • Yayıncı: ACIBADEM MEHMET ALİ AYDINLAR ÜNİVERSİTESİ