Ankilozan spondilit hastalarında nötrofil/lenfosit oranı, trombosit/lenfosit oranı ve ortalama trombosit hacminin değerlendirilmesi

Amaç: Bu çalışmanın amacı ankilozan spondilit hastalarında nötrofil/lenfosit oranı, trombosit/lenfosit oranı ve ortalama trombosit hacmini değerlendirmek ve klinik önemini araştırmaktır.Gereç ve Yöntem: Çalışmaya 51 ankilozan spondilit hastası ve 53 sağlıklı kontrol alındı. Yaş, cinsiyet, hastalık süresi, Ankilozan Spondilit Aktivite Indeksi skoru, total lökosit sayısı, nötrofil, trombosit, lenfosit sayısı, C-reaktif protein, sedimantasyon, nötrofil/lenfosit oranı, trombosit/lenfosit oranı ve ortalama trombosit hacmi değerleri retrospektif olarak analiz edildi.Bulgular: Bu çalışmada ankilozan spondilit hastalarında kontrollere göre nötrofil/lenfosit oranı, trombosit/lenfosit oranı ve ortalama trombosit hacmi değerlerinde anlamlı farklılık tespit edildi. Aktif ankilozan spondilit grubunda inaktif gruba göre nötrofil/lenfosit oranı, trombosit/lenfosit oranı ve ortalama trombosit hacmi değeri arasında anlamlı farklılık bulundu. Sonuç: Klinisyenler ankilozan spondilit hastalarında nötrofil/lenfosit oranı, trombosit/lenfosit oranı ve ortalama trombosit hacmi değerlerini hastalık aktivitesini belirlemede kullanabilirler ve bu kolayca belirlenebilir ölçümler, objektif, basit ve kolay ulaşılabilirdir, aynı zamanda herhangi bir ek maliyete de yol açmazlar.

Anahtar Kelimeler:

Ankilozan spondilit, nörofil/lenfosit oranı, trombosit/lenfosit oranı, ortalama trombosit hacmi

Evaluation of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and mean platelet volume in patients with ankylosing spondylitis

Purpose: The purpose of the present study was to evaluate neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume levels in ankylosing spondylitis patients and explore their clinical significance.Material and Methods: The study included 51 patients with AS and 53 healthy individuals. Age, sex, duration of disease, Bath Ankylosing Spondylitis Activity Index score, total white blood counts, neutrophil, platelet, lymphocyte counts, C-reactive protein, sedimantation, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values of the patients were analyzed retrospectively.Results: The present study found a significantly different neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values in patients with ankylosing spondylitis when compared to the control group. We found a significantly different neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values in patients with active phase of ankylosing spondylitis when compared to the inactive group. Conclusion: Clinicians may use neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values to evaluate disease activity in ankylosing spondylitis since these easily determinable measurements are objective, simple and readily available and also do not lead to any additional cost

Keywords:

Ankylosing Spondylitis, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean platelet volume,

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