Effect Of Metabolic Syndrome-Related Parameters On Overactive Bladder

Objective: Over active bladder (OAB) is a situation characterized by urgency which nega-tively affects quality of life. Associations have been shown between situations like age, obesity, parity, DM and hyperlipidemia with OAB. In this study, patients attending a family practice clinic without urologic symptoms had demographic and labora-tory data researched for correlation with OAB. Material and Methods: A total of 100 female patients attending a family practice clinic had de-mographic features like age, height, weight, BMI, waist/hip ratio, and waist/height ratio and labo-ratory values like blood glucose, cholesterol, TG, hemoglobin, TSH, vitamin D3 and vitamin B12 compared for their effect on the OAB-V8 survey. Results: The OAB-V8 symptom score of pa-tients was identified to have correlations with age, weight, BMI, waist circumference, waist-hip ratio, waist-height ratio and total cholesterol levels. El-evated total cholesterol, presence of more than one chronic disease, hemoglobin above 12 and central-type obesity were identified to increase OAB-V8 symptom score. Conclusion: OAB is a multifactorial disease and age, central-type obesity and more than one chronic disease may affect OAB symptoms.

Metabolik Sendrom İlişkili Parametrelerin Aşiri Aktif Mesane Üzerine Etkisi

Amaç: Aşırı aktif mesane (AAM) ani sıkışma ile karakterize ve yaşam kalitesini olumsuz etki-leyen bir durumdur. Yaş, obezite, parite, diabetes mellitus (DM), hiperlipidemi gibi durumların AAM ile ilişkisi olduğu gösterilmiştir. Bu çalışma-da aile hekimliği polkliniğine ürolojik semptom-lar dışında başvuran hastaların boy, kilo, bel ve kalça çevresi, beden kütle endeksi gibi demografik verileri ile birlikte glukoz, kolesterol, hemoglobin gibi laboratuar verilerinin AAM ile ilişkisi araştı-rılmıştır. Gereç ve Yöntemler: Aile hekimliği polikli-niğine başvuran 100 kadın hastanın yaş, boy, kg, beden kütle endeksi(BMI), bel/kalça oranı, bel/ boy oranı gibi demografik verileri ile birlikte, kan glukoz, kolesterol, trigliserit (TG), Hemoglobin, TSH, Vit D3, Vit B12 gibi laboratuar değerlerinin bu hastalara doldurulan AAM semptom skoru (OAB-V8) anketinin sonuçları ile karşılaştırıldı ve etkisi değerlendirildi. Bulgular: Hastaların OAB-V8 semptom skorunu; yaş, kg, BMI, Bel çevresi, Bel/kalça ora-nı, bel/boy oranı ve total kolesterol değerleri ile arasında korelasyon olduğu tespit edildi. Total kolesterol yüksekliği, birden çok kronik hastalık varlığı, hemoglobinin 12’den yüksek olması ve santral tip obezitenin aşırı aktif mesane semptom skoru anket puanını artırdığı saptandı. Sonuç: Aşırı aktif mesane multifaktöriyel bir hastalık olup yaş, santral tip obezite ve birden fazla kronik hastalık varlığı AAM semptomları üzerin-de etkili olabilir.

Kaynakça

1. Abrams P, Artibani W, Cardozo L, Dmochowski R, van Kerrebroeck P, Sand P, et al. “Reviewing the ICS 2002 ter-minology report: the ongoing debate.” Neurourol Urodyn 2009;28:287.

2. Haylen BT, de Ridder D, Freeman RM, Swift SE, Bergh-mans B, Lee J, et al. “An International Urogynecological As-sociation (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction.” Int Urogynecol J 2010;21:5–26. doi: 10.1007/ s00192-009-0976-9. PMID: 19937315.

3. Coyne KS, Payne C, Bhattacharyya SK, et al. “The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national commu-nity survey.” Value Health 2004;7:455-463.

4. Abrams, P., Cardozo, L., Fall, M., Griffiths, D., Rosier, P.,Ulmsten, U., et al. (2002). The standardization of termi-nology of lower urinary tract function: Report from the standardization subcommittee of the International Con-tinence Society. Neurourology and Urodynamics 2002;21; 167– 178.

5. B. Coşkun , Ö. Bayrak , M. Dinçer , K. Önem , C. Gürbüz , R. Onur “The attitudes of Urologists and Gynecologists about overactive bladder and treatment of it in Turkey: A questionnaire survey” Turk J Urol 2017;43:68-74. doi: 10.5152/tud.2016.93467. Epub 2017 Jan 27.

6. Umek W, Gleiss A, Bodner-Adler B, Reichardt B, Rinner C, Heinze G. “The role of prescription drugs in female overactive bladder syndrome-A population-wide cohort study.” Pharmacoepidemiol Drug Saf 2020;29:189-198. doi: 10.1002/pds.4920. Epub 2019 Dec 5.

7. Garnica SV, Minassian VA, Platte RO, Sartorius J. “Over-active bladder and hyperlipidemia: Is there an associa-tion?” Female Pelvic Med Reconstr Surg 2011;17:76-9. doi: 10.1097/SPV.0b013e31820e9dde. 8. Yeniel AO, Ergenoglu AM, Meseri R, Ari A, Sancar C, Itil IM. “Systemic atherosclerosis and voiding symptom.” Eur J Obstet Gynecol Reprod Biol 2017;210:306-309. doi: 10.1016/j.ejogrb.2017.01.005. Epub 2017 Jan 9.

9. Link CL, Steers WD, Kusek JW, McKinlay JB. The associa-tion of adiposity and overactive bladder appears to differ by gender: results from the Boston Area Community Health survey. J Urol 2011;185:955-63.

10. Uzun H, Zorba OU. Metabolic syndrome in female patients with overactive bladder. Urology 2012;79:72-5.

11. Matza, L. S., Thompson, C. L., Krasnow, J., Brewster-Jor-dan, J., Zyczynski, T., & Coyne, K. S. (2005). Test-retest re-liability of four questionnaires for patients with overactive bladder: The overactive bladder questionnaire (OAB-q), patient perception of bladder condition (PPBC), urgen-cy questionnaire (UQ), and the primary OAB symptom questionnaire (POSQ). Neurourology and Urodynamics 2005;24;215–225.

12. Sari Motlagh R, Hajebrahimi S, Sadeghi-Bazargani H, Joodi Tutunsaz J. “Reliability and Validation of the Inter-national Consultation on Incontinence Questionnaire in Over Active Bladder to Persian Language.” Low Urin Tract Symptoms 2015;7:99-101. doi: 10.1111/luts.12059. Epub 2014 Apr 21.

13. Stewart EF, Van Rooyen JB, Cundiff GW, Abrams P, Herzoq AR, Corey R, et al. “Prevalence and burden of overactive bladder in the United States.” World J Urol 2003; 20:327e36.

14. Irwin DE, Milsom I, HunsKaar S, Reilly K, Kopp Z, Her-schorn S, et al. “Population-based survey of urinary incon-tinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study.” Eur Urol 2006;50:1306e14.

15. Lee YS, Lee KS, Jung JH, Han DH, Oh SJ, Seo JT, et al. “Prevalence of overactive bladder, urinary incontinence, and lower urinary tract symptoms: results of Korean EPIC study”. World J Urol 2011;29:185e90.

16. Homma Y, Yamaguchi O, Hayashi K. “Neurogenic Bladder Society Committee. An epidemiological survey of overac-tive bladder symptoms in Japan.” BJU Int 2005;96:1314e8.

17. Lapitan MC, Chye PL. Asia-Pacific Continence Advisory Board. “The epidemiology of overactive bladder among females in Asia: a questionnaire survey.” Int Urogynecol J Pelvic Floor Dysfunc 2001;12:226e31.

18. Yu HJ, Liu CY, Lee KL, Lee WC, Chen TH. “Overactive bladder syndrome among community- dwelling adults in Taiwan: prevalence correlates, perception, and treatment seeking”. Urol Int 2006; 77:327e33.

19. Khullar V, Chapple C, Gabriel Z, Dooley JA. “The effects of antimuscarinics on health-related quality of life in overac-tive bladder: a systematic review and meta-analysis. Urol-ogy 2006;68:38-48.

20. Abrams P, Kelleher CJ, Kerr LA, Rogers RG. “Overactive bladder significantly affects quality of life.” Am J Manag Care 2000;6: S580e90.

21. Peterson AC, Sehgal A, Crump RT, Baverstock R, Suther-land JM, Carlson K. “Evaluating the 8- item overactive bladder questionnaire (OAB-v8) using item response the-ory.” Neurourol Urodyn 2018;37:1095-1100. Doi:10.1002/ nau.23420. Epub 2017 Oct 4.

22. Palma T, Raimondi M, Souto S, Fozzatti C, Palma P, Riccet-to C. “Correlation between age and overactive bladder symptoms in young women in Brazil”. Actas Urol Esp 2013; 37:156–161. doi: 10.1016/j. acuro.2012.07.009 PMID: 23411070.

23. Liu RT, Chung MS, Lee WC, Chang SW, Huang ST, Yang KD, et al. Prevalence of overactive bladder and associated risk factors in 1359 patients with type 2 diabetes. Urolo-gy 2011;78:1040–1045. doi: 10.1016/j.urology.2011.05.017 PMID: 21958505.

24. Fitzgerald MP, Link CL, Litman HJ, Travison TG, McKin-lay JB. Beyond the lower urinary tract: the association of urologic and sexual symptoms with common illnesses. Eur Urol 2007;52:407–415. PMID: 17382458. 25. Wen JG, Li JS, Wang ZM, Huang CX, Shang XP, Su ZQ, Lu YT, Suo ZH, Wang Y, Qin GJ, Zhang WX, Heesak-kers JP. “The prevalence and risk factors of OAB in middle- aged and old people in China.” Neurourol Urodyn 2014;3:387-91. doi: 10.1002/nau.22429. Epub 2013 Jun 13.

26. Palma T, Raimondi M, Souto S, Fozzatti C, Palma P, Riccet-to C. “Correlation between body mass index and overactive bladder symptoms in pre-menopausal women.” Rev Assoc Med Bras (1992). 2014;60:111-7.

27. Esen Yeşil, Merve Özdemir, Gözde Arıtıcı Çolak, Em-ine Aksoydan “Evaluatıon Of The Relationshıp Between Waıst Heıght Ratıo And Other Anthropometrıc Measures In The Risk Of Chronic Diseases” Acu Sağlık Bil Derg 2019; 10:241-246. https://Doi.Org/10.31067/ 0.2018.78 28-Lai .

28. HH, Helmuth ME, Smith AR, Wiseman JB, Gillespie BW, Kirkali Z; Symptoms of Lower Urinary Tract Dysfunc-tion Research Network (LURN). “Relationship Between Central Obesity, General Obesity, Overactive Bladder Syndrome and Urinary Incontinence Among Male and Fe-malePatients Seeking Care for Their Lower Urinary Tract Symptoms.” Urology 2019;123:34-43. doi: 10.1016/j.urolo-gy.2018.09.012. Epub 2018 Oct 28.

29. Lee RK, Chung D, Chughtai B, Te AE, Kaplan SA. “Cen-tral obesity as measured by waist circumference is predic-tive of severity of lower urinary tract symptoms.” BJU Int 2012;110:540-5. doi:10.1111/j.1464-410X.2011.10819.x. Epub 2012 Jan 13.

30. Son H, Choi WS, Paick JS, Park WH. “Detrusor Overactivity in Hyperchoelsterolemia Rats.” Low Urin Tract Symptoms 2012;4;16-20. doi: 10.1111/j.1757-5672. 2011.00124.x.

Kaynak Göster

Yeni Üroloji Dergisi
  • ISSN: 1305-2489
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 2005

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