Subklinik Hipotiroidi Nedir? Tedavi Edilmeli midir?

Bireylerin serum serbest tiroid hormon düzeyleri normal değerlerde iken tiroid uyarıcı hormon düzeyinin yüksek olması toplumda oldukça sık görülen bir durumdur ve bu durum subklinik hipotiroidi olarak tanımlanmaktadır. Subklinik hipotiroidi genel populasyonda %3-8 oranında görülmekte, prevalansı yaşla birlikte artmakta ve kadınlarda daha sık görülmektedir. Subklinik hipotiroidinin en önemli sonucu aşikar hipotiroidiye ilerlemedir. Subklinik hipotiroidi ile kardiyovasküler hastalıklarda artış ve bilişsel fonksiyonlarda azalma arasındaki ilişki kesin olarak gösterilememiştir. Bu nedenle levotiroksin tedavisinin faydaları konusunda da fikir birliği bulunmamaktadır. Genel olarak tiroid uyarıcı hormon düzeyi 10 mU/L’nin üzerinde olanlara tedavi önerilmekte, bu düzeylerin altında olanlarda tedavinin kişiselleştirilmesi, hastaların risk faktörleri ve yaşları göz önünde bulundurularak değerlendirilmeleri önerilmektedir.

Anahtar Kelimeler:

Subklinik hipotiroidi, tiroid fonksiyon testleri

What is Subclinical Hypothyroidism? It should be treated?

Although serum free thyroid hormone levels are normal, high levels of thyroid stimulating hormone is more frequent condition in population and is defined as subclinical hypothyroidism. In general population 3-8 % is seen. Prevalance of subclinical hypothyroidism increases with age and is more common in women. Most important consequence of subclinical hypothyroidism is progression to overt hypothyroidism. increased risk of cardiovascular disease and a decreased cognitive functions due to subclinical hypothyroidism remains uncertain. Therefore, the consensus about the benefits of levothyroxine treatment is not available. In general, the level of thyroid stimulating hormone 10 mU/L, those on treatment are recommended, which are below the level of treatment to be personalized, consideration of patient age, risk factors are recommended.

Keywords:

Subclinical hypothyroidism, thyroid function tests,

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