İntestinal Endometriozis Tanılı Olguların Klinikopatolojik Bulgularının Değerlendirilmesi

Ekstrapelvik endometriozis, endometrial glandüler ve/veya stromal komponentin ekstrauterin lokalizasyonlarda bulunması olarak tanımlanmakta olup en sık gastrointestinal sistemde görülmektedir. Biyopsi örneğinde endometrial gland ve stroma varlığında endometriozis yönünde tanı vermek zor olmasa da, endoskopik biyopsi materyalleri genellikle endometriozis tanısı için yeterli doku içermemektedir. Çalışmamızda intestinal endometriozis olgularımızda, intestinal epitelde ve endometriozis odağında gözlenen histomorfolojik bulgular belirlenmiş ve endometriozis odağının bulunduğu lokalizasyon ile ilişkisi araştırılmıştır. Endometriotik odağın lokalize olduğu intestinal tabaka ile intestinal epitelde görülen mikroskopik değişikliklerin birbiri ile ilişkili olduğu saptanmış olup, bu mikroskopik değişikliklerin inflamatuar bağırsak hastalığı, iskemik kolit, karsinoma gibi antitelerin taklitçisi olabileceği dikkat çekmiştir.

Anahtar Kelimeler:

Endometriozis, İntestinal endometriozis, Patoloji

Evaluation of Clinicopathological Findings of Cases Diagnosed With Intestinal Endometriosis

Extrapelvic endometriosis is defined as the presence of endometrial glandular and/or stromal components in extrauterine localizations and is most commonly seen in the gastrointestinal tract. Although it is not difficult to diagnose endometriosis in the presence of an endometrial gland and stroma, endoscopic biopsy materials generally do not contain sufficient tissue for the diagnosis of endometriosis. In our study, histomorphological findings observed in the intestinal epithelium and endometriosis focus were determined in our intestinal endometriosis cases. The relationship between these findings and the localization of the endometriosis focus was investigated. It has been determined that the intestinal layer where the endometriotic focus is localized and the microscopic changes seen in the intestinal epithelium are related to each other, and it has been noted that these microscopic changes may mimic entities such as inflammatory bowel disease, ischemic colitis, and carcinoma.

Keywords:

Endometriosis, Intestinal endometriosis, Pathology,

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