Orhan ERMAN, Hasan TÜRKEZ, Ümit İNCEKARA

Biomonitoring of the genotoxic potentials of two edible insects species in vitro

Bu araştırmada, suda çözünür Saga ephippigera ephippigera Fischer de Waldheim, 1846 ve Callimenus dilatatus (Stal, 1876) (Orthoptera) ekstrelerinin insan kan kültürleri üzerine genotoksik potansiyelleri değerlendirilmiştir. In vitro şartlarda sulu ekstreler tarafından oluşturulan DNA ve kromozom hasarlarının tespitinde kromozom aberasyonu (KA) ve mikroçekirdek (MÇ) testleri kullanılmıştır. Ekstreler sekiz farklı konsantrasyonda (1, 5, 10, 20, 25, 50, 75 ve 100 mg/l) kültürlere uygulanmıştır. Sonuçlar, test edilen konsantrasyonlarda bu ekstrelerin genotoksik etkilerinin bulunmadığını ortaya koymuştur. Yenilebilir böceklerin mutajenite ve karsinojenite ile ilgili potansiyel sağlık risklerinin değerlendirilmesinde in vitro genotoksisitesinin biyolojik izlenmesinin faydalı olabileceği önerilmiştir.

Yenilebilir iki böcek türünün genotoksisite potansiyellerinin in vitro şartlarda biyolojik izlenmesi

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