Erkan KARADAŞ, Nursel METİN, İhsan YAMAN

Elazığ' da bir keçide gözlenen ilk paratüberküloz olgusunda patolojik bulgular

Pathological findings in the first case of caprine paratuberculosis (Johne's disease) in Elazığ

Caprine paratuberculosis (Johne's disease) was diagnosed according to pathomorphological findings in a 5-year-old indigenous female hairy goat in Elazig. Diagnosis was confirmed by demonstration of Mycobacterium avium subspecies paratuberculosis (M.a. paratuberculosis) in the intestinal smears and tissue sections stained with the Ziehl-Neelsen (ZN) method, and also detection of specific M.a. paratuberculosis DNA by the Polymerase Chain Reaction (PCR).

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1.Alibaflo¤lu, M., Demirer, F., Yücel, N.: Paratüberkülozda AllerjikReaksiyonlar›n Patoloik Bulgularla Uygunluk Derecesi ÜzerindeAraflt›rma. A.Ü. Vet. Fak. Derg., 1969: 16: 236-256.
2.Buergelt, C.D., Hall, C., McEntee, K., Duncan, J.R.: PathologicalEvaluation of Paratuberculosis in Naturally Infected Cattle. Vet.Path., 1978: 15: 196-207.
3.Massone, A.R., Itagaki, S., Ibargoyan, G.S., Martin, A.A., Doi, K.and Gimeno, E.J.: Demonstration of MycobacteriumParatuberculosis in Tissue Sections: Comparative Studies ofHistological and Immunohistochemical Methods. Isr. J. Vet. Med.1991: 46: 48-50.
4.Saxegaard, F.: Experimental Infection of Calves with onApparently Specific Goat Pathogenic Strain of MycobacteriumParatuberculosis. J. Comp. Path., 1990: 102: 149-156.
5.Çiftçi, M.K., Hatipo¤lu, F.: Dört Olguda Gözlenen KoyunParatüberkülozu Olaylar› Üzerinde Patolojik ‹ncelemeler.Veterinarium, 1991: 2: 32-36.
6.Carrigan, M.J. And Seaman, J.T.: The Pathology of Johne’sDisease in Sheep. Aust. Vet. J., 1990: 67: 47-50.
7.Hakioğlu, F.: Bir Koyunda Tesbit Edilen Paratüberküloz Vakas›.Pen. Vet. Kont. Arfl. Ens. Derg., 1968: 1: 144-145.
8.Jatkar, P.R., Kumar, D., Kayum, A., Sani, S.S., Gahlat, G.C. andJairath, L.K.: Epidemiological Study of Johne’s Disease in SheepRajasthan. Ind. J. Anim. Sci., 1990: 60: 425-426.
9.Mustafa, A.A. and Mugadmi, V.E.: First Report ofParatuberculosis (Johne’s Disease) in Libya. Vet. Rec., 1986:118: 729.
10.Reddy, K.P., Sriraman, P.K., Gopal, N.R. and Rao, P.R.:Pathology of Johne’s Disease in Sheep. Ind. Vet. J., 1984: 61:179-184.
11.Williams, E.S., Spraker, T.R., Schoonveld, G.G.: Paratuberculosis(Johne’s Disease) in Bighorn Sheep and Rocky Mountain Goat inColorado. J. Wildl. Dis., 1979: 15: 221-227.
12.Alibaşoğlu, M., Ertürk, E., Yücel, N.: Türkiye’de Rastlanan ilk KeçiParatüberküloz Olaylar› Üzerinde Patolojik incelemeler. A.ü. Vet.Fak. Derg. 1973: 20: 43-63.
13.Fodstad, F.H. and Gunnarsson, E.: Post-mortem Examination inthe Diagnosis of Johne’s Disease in Goats. Acta. Vet. Scandin.,1979: 20: 157-167.
14.Gezon, H.M., Bither, H.D., Gibbs, H.C., Acker, E.T., Hanson,L.A., Thompson, J.K. and Jonpenson, R.D.: Idendification andControl of Paratuberculosis in a Large Goat Herd. Am. J. Vet.Res., 1988: 49: 1817-182
15.Koul, G.L., Sumvanshi, S. and Biswas, J.L.: Mortality Pattern inPasmina Goats. Ind. Vet. J., 1988: 65: 847-849.
16.Lenghaus, C., Badman, R., Gillick, J.L.: Johne’s Disease in Goats.Aust. Vet. J., 1977: 53: 460.
17.Shimshany, A. and Bar-Moshe, B.: A Case of Johne’s Disease inan Israeli Saanen Goat. Refauh Vet., 1972: 29: 35-37.
18.Yeşildere, T., Alibaşoğlu, M., Çalışkan, A.U., Bilal, T.: MarmaraBölgesindeki Bir Zirai Üretim ‹flletmesinde Rastlanan KeçiParatuberculosisi Olaylar› Üzerinde Patolojik ‹ncelemeler. ‹.Ü. Vet.Fak. Derg., 1984: 10: 15-30.
19.Williams, E.S., Snyder, S.P. and Martin, K.L.: Pathology ofSpontaneous and Experimental Infection of North American WildRuminants with Mycobacterium Paratuberculosis. Vet. Path.,1983: 20: 274-291.
20.Jessup, D.A., Abbas, B., Behymer, D., Goyan, P.:Paratuberculosis in Tule Elk in California. J. Am. Vet. Med.Assoc., 1981: 179: 1252-1254.
21.Jubb, K.V.F., Kennedy, P.C. and Palmer, N.: Pathology ofDomestic Animals. Third Edit, Vol. 2, Academic Press, Inc.,Orlando, Florida, 1985.
22.Lepper, A.W.D., Jarret, R.G. and Lewis, W.M.: The Effect ofDifferent Levels of Iron Intake on the Multiplication ofMycobacterium Paratuberculosis in C 57 and C3H Mice. Vet.Microbiology, 1988: 16: 369-383.
23.Momotani, E., Whipple, E., Theirmann, A. and Cheville, N.: Roleof M. Cells and Macrophages in the Entrance of MycobacteriumParatuberculosis into Domes of Ileal Peyer’s Patches in Calves.Vet. Path., 1988: 25: 131-137.
24.Clarke, C.J. and Little, D.: The Pathology of OvineParatuberculosis: Gross and Histological Changes in the Intestineand Other Tissues. J. Comp. Path., 1966: 114: 419-437.
25.Sezginer, R.İ.: S›¤›rlar›n Paratüberkülozu., Ehli Hayvanlarda ‹ntaniHastal›klar. 1928: 11: 252-259 Al›nm›flt›r: Alibaflo¤lu, M.,Ertürk, E., Yücel, N.: Türkiye’de Rastlanan ‹lk KeçiParatüberküloz Olaylar› Üzerinde Patolojik ‹ncelemeler. A.Ü. Vet.Fak. Derg., 1973: 20: 43-63.
26.Çetinkaya, B.: F›rat Üniversitesi, Veteriner Fakültesi, MikrobiyolojiAnabilim Dal› Ö¤retim Üyesi: Kiflisel Görüflme, 1997