Congenital tuberculosis in a 25-day-old female calf

  A female calf, housed in a dairy intensive-system farm, suddenly died 25 days after birth. Routine necropsy revealed multiple variably sized white to yellowish nodules in the lungs. Histopathological diagnosis showed severe granulomatous pneumonia with acid-fast bacilli; Mycobacterium bovis was confirmed by polymerase chain reaction and culture isolation. Congenital tuberculosis was diagnosed based on these findings. The calf probably acquired the infection from her mother through aspiration of the amniotic fluid. The aim here is to describe the morphological lesions and complementary confirmation of congenital tuberculosis in a young female calf.

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  • Phillips CJ, Foster CR, Morris PA, Teverson R. The transmission of Mycobacterium bovis infection to cattle. Res Vet Sci 2003; 74: 1-15.
  • O’Reilly LM, Daborn CJ. The epidemiology of Mycobacterium bovis infections in animals and man: a review. Tuber Lung Dis 1995; 76: 1-46.
  • Hosek J, Svastova P, Moravkova M, Pavlik I, Bartos M. Methods of mycobacterial DNA isolation from different biological material: a review. Vet Med (Praha) 2006; 51: 180-192.
  • Domingo M, Vidal E, Marco A. Pathology of bovine tuberculosis. Res Vet Sci 2014; 97: S20-S29.
  • Dungworth DL. The respiratory system. In: Jubb KVF, Kennedy PC, Palmer N, editors. Pathology of Domestic Animals. 3rd ed. San Diego, CA, USA: Academic Press; 1985. pp. 498-503.
  • Talbot EA, Williams DL, Frothingham R. PCR identification of Mycobacterium bovis BCG. J Clin Microbiol 1997; 35:566-9.
  • NOM-056-ZOO-1995. Especificaciones tecnicas para las pruebas diagnosticas que realicen los laboratorios de pruebas aprobados en materia zoosanitaria. Diario oficial de la federación 1999; 106-116 (in Spanish).
  • Ozyigit M, Senturk S, Akkoc A. Suspected congenital generalised tuberculosis in a newborn calf. Vet Rec 2007; 160: 307-308.
  • Vural SA, Tunca R. Generalized tuberculosis in a 45 day-old calf. Dtsch Tierarztl Wochenschr 2001; 108: 468-470.
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK