= %0.3) uygun bulunmuştur. Toprak üstü kısımlarından hesaplanan klorojenik asit miktarları ise sırasıyla %1.047±0.0007, %0.751±0.0033, %0.31±0.0085, %0.488±0.0051 olarak tayin edilmiştir. Tüm numunelerin yapraklarında bulunan klorojenik asit miktarı toprak üstü kısımlarındakinden fazladır. Bu çalışma göstermiştir ki yapraklar yerine toprak üstü kısımların kullanılması uygun değildir. Urtica dioica L. (Urticacea) is widely distributed throughout the temperate regions of the world. Leaves of the plant recommended not only for the complaints associated with rheumatoid arthritis, cardiovascular diseases and diabetes but also have antiviral, antioxidant, anti-inflammatory activities. It is also used as traditional medicine as panacea in Turkey. Despite, U. dioica leaf is monographed in European Pharmacopeia as “Nettle Leaf – Urtica folium” and standardized by liquid chromatography for its chlorogenic acid content; aerial parts of plants are sold instead of leaves at the herbal shops for medical purposes in Turkey. The objective of our study is to determine quality of samples and compare the chlorogenic acid amount in aerial parts and leaves collected from different localities of Anatolia. Extraction procedure was employed according to European Pharmacopeia 6.0. p-Coumaric acid was used as internal standart. RP-HPLC was performed in order to determine chlorogenic acid amounts. The leaf samples collected from Düzce, Maraş, Işık Mountain and Palandöken Mountain has possesed highest chlorogenic acid amounts 1.91±0.0003%, 1.156±0.0019%, 0.67±0.00068%, 0.63±0.0024% respectively. However amount of chlorogenic acid in aerial parts of same samples has been found 1.047±0.0007%, 0.751±0.0033%, 0.31±0.0085%, 0.488±0.0051% respectively. Results indicate that in all samples, chlorogenic acid content has been found higher in leaves than aerial parts. Present study revealed that usage of the aerial parts instead of leaves for medical purposes isn’t appropriate.">
[PDF] Türkiye’nin Farklı Bölgelerinden Toplanmış Urtica dioica L. Örneklerinin Kalite Değerlendirmesi | [PDF] Quality Assesment of Urtica dioica L. Samples Collected from Different Locations of Turkey
= %0.3) uygun bulunmuştur. Toprak üstü kısımlarından hesaplanan klorojenik asit miktarları ise sırasıyla %1.047±0.0007, %0.751±0.0033, %0.31±0.0085, %0.488±0.0051 olarak tayin edilmiştir. Tüm numunelerin yapraklarında bulunan klorojenik asit miktarı toprak üstü kısımlarındakinden fazladır. Bu çalışma göstermiştir ki yapraklar yerine toprak üstü kısımların kullanılması uygun değildir.">
= %0.3) uygun bulunmuştur. Toprak üstü kısımlarından hesaplanan klorojenik asit miktarları ise sırasıyla %1.047±0.0007, %0.751±0.0033, %0.31±0.0085, %0.488±0.0051 olarak tayin edilmiştir. Tüm numunelerin yapraklarında bulunan klorojenik asit miktarı toprak üstü kısımlarındakinden fazladır. Bu çalışma göstermiştir ki yapraklar yerine toprak üstü kısımların kullanılması uygun değildir. Urtica dioica L. (Urticacea) is widely distributed throughout the temperate regions of the world. Leaves of the plant recommended not only for the complaints associated with rheumatoid arthritis, cardiovascular diseases and diabetes but also have antiviral, antioxidant, anti-inflammatory activities. It is also used as traditional medicine as panacea in Turkey. Despite, U. dioica leaf is monographed in European Pharmacopeia as “Nettle Leaf – Urtica folium” and standardized by liquid chromatography for its chlorogenic acid content; aerial parts of plants are sold instead of leaves at the herbal shops for medical purposes in Turkey. The objective of our study is to determine quality of samples and compare the chlorogenic acid amount in aerial parts and leaves collected from different localities of Anatolia. Extraction procedure was employed according to European Pharmacopeia 6.0. p-Coumaric acid was used as internal standart. RP-HPLC was performed in order to determine chlorogenic acid amounts. The leaf samples collected from Düzce, Maraş, Işık Mountain and Palandöken Mountain has possesed highest chlorogenic acid amounts 1.91±0.0003%, 1.156±0.0019%, 0.67±0.00068%, 0.63±0.0024% respectively. However amount of chlorogenic acid in aerial parts of same samples has been found 1.047±0.0007%, 0.751±0.0033%, 0.31±0.0085%, 0.488±0.0051% respectively. Results indicate that in all samples, chlorogenic acid content has been found higher in leaves than aerial parts. Present study revealed that usage of the aerial parts instead of leaves for medical purposes isn’t appropriate.">
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