Betül Sözeri, Funda Baştuğ, Hülya Nalçacıoğlu, Hakan Poyrazoğlu, Ayşenur Paç Kısaarslan, Ruhan Düşünsel, Zübeyde Gündüz, Sibel Yel, Nihal Şahin, Sümeyra Özdemir Çiçek

Elemental mercury intoxication in 7 patients admitted to a pediatric rheumatology clinic

Mercury (Hg) is a toxic heavy metal that can be classified into threegroups; organic (methyl), inorganic (mercuric), and elemental (metallic)mercury(Hg0). Mercury intoxication occurs mostly with the elemental formwhich can potentially damage the function of any organ, or any subcellularstructure. The target organ of mercury is the brain, but peripheral nervefunction, renal function, immune function, endocrine and muscle function,and several types of dermatitis have been described. We present 7 patientsadmitted to a pediatric rheumatology clinic with severe extremity pain. Oneof the patients had acrodynia, two of them had hypertension, two of themhad tubulopathy, and three of them had neuropathy. The treatments wereDimercaptosuccinic acid and metalcaptase. In this report, we emphasize thatmercury intoxication should be kept in mind with unexplained extremity pain.Timely diagnosis and treatment may prevent severe morbidity and mortality

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1. Goldman LR, Shannon MW; American Academy of Pediatrics: Committee on Environmental Health. Technical report: mercury in the environment: implications for pediatricians. Pediatrics 2001; 108: 197-205.
2. Counter SA, Buchanan LH. Mercury exposure in children: a review. Toxicol Appl Pharmacol 2004; 198: 209-230.
3. Akyildiz B, Kondolot M, Kurtoğlu S, Konuşkan B. Case series of mercury toxicity among children in a hot, closed environment. Pediatr Emerg Care 2012; 28: 254-258.
4. Carman KB, Tutkun E, Yilmaz H, et al. Acute mercury poisoning among children in two provinces of Turkey. Eur J Pediatr 2013; 172: 821-827.
5. MacLehose R, Pitt G, Will S, et al. Mercury contamination incident. J Public Health Med 2001; 23: 18-22.
6. Bose-O’Reilly S, McCarty KM, Steckling N, Lettmeier B. Mercury exposure and children’s health. Curr Probl Pediatr Adolesc Health Care 2010; 40: 186-215.
7. Celebi N, Canbay O, Aycan IO, Sahin A, Aypar U. Mercury intoxication and neuropathic pain. Paediatr Anaesth 2008; 18: 440-442.
8. Beck C, Krafchik B, Traubici J, Jacobson S. Mercury intoxication: It still exists. Pediatr Dermatol 2004; 21: 254-259.