İsmail SAYGIN, Emel ÇAKIR, Mustafa Emre ERCİN

Choroid plexus papilloma in extragonadal teratoma with predominantly neurogenic elements: a case report and review of the literature

Background. Teratoma is a germ cell tumor that develops gonadal or extragonadal. Benign or malign somatic tumors can develop in teratoma. Choroid plexus papilloma is a benign, grade I intraventricular neoplasm that occur mostly in children. Choroid plexus papilloma in a teratoma is not often seen. Case. We present the fifth case of a choroid plexus papilloma in a teratoma in the English literature. It was extragonadal and localized on the right side of the neck. It included only neuroglial tissue.Conclusion. It is important to separate a teratoma with normal choroid plexus from a teratoma with choroid plexus tumor. Pathologists need to be aware of this entity in the distinction from other papillary neoplasms that may be primary or metastatic.

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1. Nelson BL. Teratoma. In: Thompson LDR, Wenig BM (eds). Diagnostic Pathology: Head and Neck (2nd ed). Philadelphia: Elsevier, 2016: 409-411.

2. Maitra A. Diseases of infancy and childhood. In: Kumar V, Abbas AK, Aster JC (eds). Robbins and Cotran Pathologic Basis of Disease (9th ed). Philadelphia: Saunders, 2015: 474-475.

3. Hasiotou M, Vakaki M, Pitsoulakis G, et al. Congenital cervical teratomas. Int J Pediatr Otorhinolaryngol 2004; 68: 1133-1139.

4. Paulus W. Brandner S. Hawkins C. Tihan T. Choroid plexus tumours. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds). WHO Classification of Tumours of the Central Nervous System (Medicine) (4th ed). World Health Organization. Lyon: International Agency for Research on Cancer, 2016: 124-129.

5. Khade S, Shenoy A. Ectopic choroid plexus papilloma. Asian J Neurosurg 2018; 13: 191-194.

6. Kihara A, Lihara K, Murata K, Kitagawa M, Horiuchi H. Choroid plexus papilloma arising in a mature cystic teratoma of the ovary: a short case report and literature review. Pathol Int 2015; 65: 563-565.

7. Shah A, Latoo S, Ahmed I, Malik AH. Head and neck teratomas. J Maxillofac Oral Surg 2009; 8: 60-63.

8. Akbulut M, Kelten EC, Ege CB. Mature cystic teratoma with predominately neurogenic elements - case report. Aegean Pathol J 2006; 3: 18-20.

9. Sharma S, Dawson L, Mandal AK. Primary retroperitoneal teratoma with predominant neurogenic elements masquerading as adrenal tumor. Turk J Pathol 2019; 35: 69-73.

10. Williams K, Chernetsova E, Michaud J, El Demellawy D. Neurogenic ovarian vyst: arare, monodermal teratoma. Pediatr Dev Pathol 2015; 18: 341-342.

11. Catala M. Embryonic and fetal development of structures associated with the cerebro-spinal fluid in man and other species. Part I: the ventricular system, meninges and choroid plexuses. Arch Anat Cytol Pathol 1998; 46: 153-169.

12. Ikota H, Tanaka Y, Yokoo H, Nakazato Y. Clinicopathological and immunohistochemical study of 20 choroid plexus tumours: their histological diversity and the expression of markers useful for differentiation from metastatic cancer. Brain Tumor Pathol 2011; 28: 215-221.

13. Hasselblatt M, Böhm C, Tatenhorst L, et al. Identification of novel diagnostic markers for choroid plexus tumors: amicroarray-based approach. Am J Surg Pathol 2006; 30:66-74

14. Von Gunten M, Burger H, Vajtai I. Choroid plexus papilloma developing in a dermoid cyst of ovary. Histopathology 2006; 49: 204-205.

15. Quadri AM, Ganesan R, Hock YL, Karim SN, Hirschowitz L. Malignant transformation in mature cystic teratoma of the ovary: three cases mimicking primary ovarian epithelial tumors. Int J Surg Pathol 2011; 19: 718-723.

16. Dessauvagie BF, Ruba S, Robbins PD. Choroid plexus papilloma arising in a mature cystic teratoma of a 32-year-old female. Pathology 2013; 45: 88-89.