Value of shear wave elastography by virtual touch tissue imaging quantification in patients with diffuse thyroid gland pathology

Value of shear wave elastography by virtual touch tissue imaging quantification in patients with diffuse thyroid gland pathology

Background/aim: This study was performed to assess the diagnostic accuracy of shear wave elastography by virtual touch tissue imagingquantification in patients with diffuse thyroid gland pathology and to differentiate Graves’ disease from Hashimoto’s thyroiditis.Materials and methods: Thirty patients with Hashimoto’s thyroiditis and 22 patients with Graves’ disease were evaluated withconventional ultrasonography and shear wave elastography by virtual touch tissue imaging quantification. Thirty healthy participantsformed the control group. Ten elastographic measurements of each thyroid lobe were performed in all three study groups. The meanshear wave velocity was calculated and compared between the patients and controls.Results: The mean shear wave velocity of the controls (1.92 ± 0.14 m/s) was significantly lower than that of the patients with Graves’disease (2.71 ± 0.22 m/s) and Hashimoto’s thyroiditis (2.50 ± 0.20 m/s). Patients with Graves’ disease had significantly higher shear wavevelocities than those with Hashimoto’s thyroiditis (P < 0.001).Conclusion: Shear wave elastography by virtual touch tissue imaging quantification can be used to discriminate a normal thyroid glandfrom diffuse thyroid gland pathology after conventional sonography and may assist in the diagnosis of Graves’ disease and Hashimoto’sthyroiditis.

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  • Cipolla C, Sandonato L, Graceffa G, Fricano S, Torcivia A, Vieni S, Latteri S, Latteri MA. Hashimoto thyroiditis coexistent with papillary thyroid carcinoma. Am Surg 2005; 71: 874-878.
  • Sakiyama R. Thyroiditis: a clinical review. Ann Fam Physician 1993; 48: 615-621.
  • Hemminki K, Li X, Sundquist J. The epidemiology of Graves’ disease: evidence of a genetic and an environmental contribution. J Autoimmun 2010; 34: 307-313.
  • Dudea SM, Botar-Jid C. Ultrasound elastography in thyroid disease. Med Ultrason 2015; 17: 74-96.
  • Hekimoglu K, Yildirim Donmez F, Arslan S, Ozdemir A, Demir C, Yazici C. The role of shear wave elastography in the diagnosis of chronic autoimmune thyroiditis. Med Ultrason 2015; 17: 322-326.
  • Cantisani V, Lodise P, Grazhdani H, Mancuso E, Maggini E, Di Rocco G, D’Ambrosio F, Calliada F, Redler A, Ricci P et al. Ultrasound elastography in the evaluation of thyroid pathology. Current status. Eur J Radiol 2014; 83: 420-428.
  • Zhang H, Shi Q, Gu J, Jiang L, Bai M, Liu L, Wu Y, Du L. Combined value of Virtual Touch tissue quantification and conventional sonographic features for differentiating benign and malignant thyroid nodules smaller than 10 mm. J Ultrasound Med 2014; 33: 257-264.
  • Cebi Olgun D, Korkmazer B, Kılıç F, Dikici AS, Velidedeoğlu M, Aydoğan F, Kantarcı F, Yılmaz MH. Use of shear wave elastography to differentiate benign and malignant breast lesions. Diagn Interv Radiol 2014; 20: 239-244.
  • Han R, Li F, Wang Y, Ying Z, Zhang Y. Virtual touch tissue quantification (VTQ) in the diagnosis of thyroid nodules with coexistent chronic autoimmune Hashimoto’s thyroiditis: a preliminary study. Eur J Radiol 2015; 84: 327-331.
  • Sporea I, Sirli R, Bota S, Vlad M, Popescu A, Zosin I. ARFI elastography for the evaluation of diffuse thyroid gland pathology: preliminary results. World J Radiol 2012; 28: 174- 178.
  • Fukuhara T, Matsuda E, Izawa S, Fujiwara K, Kitano H. Utility of shear wave elastography for diagnosing chronic autoimmune thyroiditis. J Thyroid Res 2015; 2015: 164548.
  • Bai M, Du L, Gu J, Li F, Jia X. Virtual touch tissue quantification using acoustic radiation force impulse technology: initial clinical experience with solid breast masses. J Ultrasound Med 2012; 31: 289-294.
  • Ruchala M, Szczepanek-Parulska E, Zybek A, Moczko J, Czarnywojtek A, Kaminski G, Sowinski J. The role of sonoelastography in acute, subacute and chronic thyroiditis: a novel application of the method. Eur J Endocrinol 2012; 166: 425-432.
  • Menzilcioglu MS, Duymus M, Gungor G, Citil S, Sahin T, Boysan SN, Sarica A. The value of real-time ultrasound elastography in chronic autoimmune thyroiditis. Br J Radiol 2014; 87: 20140604.
  • Friedrich-Rust M, Romenski O, Meyer G, Dauth N, Holzer K, Grünwald F, Kriener S, Herrmann E, Zeuzem S, Bojunga J. Acoustic radiation force impulse imaging for evaluation of the thyroid gland. Ultrasonics 2012; 52: 69-74.
  • Sporea I, Vlad M, Bota S, Sirli RL, Popescu A, Danila M, Sendroiu M, Zosin I. Thyroid stiffness assessment by acoustic radiation force impulse elastography (ARFI). Ultraschall Med 2011; 32: 281-285.
  • Dayan CM, Daniels GH. Chronic autoimmune thyroiditis. N Engl J Med 1996; 335: 99-107.
  • Volpe R. Autoimmune thyroiditis. In: Braveman LE, Utiger RD, editors. Werner and Ingbar’s The Thyroid: A Fundamental and Clinical Text. 6th ed. Philadelphia, PA, USA: J.B. Lippincott; 1991, p. 921.