The prevalence of complementary and alternative medicine use among Turkish patients with primary headache

The prevalence of complementary and alternative medicine use among Turkish patients with primary headache

Background/aim: The use of complementary and alternative medicine (CAM) is common in patients with primary headache. However, no study has been reported in which standardized modalities were questioned in a Turkish population. The aim of the present study was to investigate the frequency of CAM use and factors related to it in these patients. Materials and methods: Patients with a diagnosis of primary headache were included in this cross-sectional observational study. Demographic and disease specific characteristics were recorded. The use and effect of 15 CAM modalities were evaluated in accordance with the Traditional and Complementary Medicine Regulations. The patients were categorized into two groups according to their use of CAM procedures. Logistic regression analysis was further performed to assess the association between CAM use and related factors. Results: One hundred twenty patients [101 (84.2%) female, mean age 38.20 ± 12.24 years] were included. Use of CAM was reported in 33.3% of the patients. The most frequently used CAM modalities were phytotherapy (37.5%), cupping (27.5%), and chiropractic adjustment (17.5%). Compared with nonusers, CAM users showed a longer duration of disease (respectively mean 5.68 ± 4.96 years and 10.97 ± 8.57 years, p = 0.000). There were no differences with respect to age, sex, education, presence of systemic disease, headache subtypes, number of headache days in a month, or headache severity. Patients who underwent cupping reported that they benefited more than those who tried phytotherapy and multiple CAM methods (respectively 45.5%, 33.3%, 16.6%, p = 0.039). Subsequently, the logistic regression analysis showed a significant association between only disease duration and CAM use [respectively p value, OR (95% CI), and confidence intervals = 0.002 (1.143 (1.050–1.243)]. Conclusion: Our results suggest that Turkish patients with primary headache, especially those with long disease duration, use CAM modalities. Larger population-based studies are required to clarify the safety and efficacy of these methods.Key words: Complementary and alternative medicine, primary headache, prevalence

___

  • 1. Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders. 3rd ed. Cephalalgia 2018; 38 (1): 1-211. doi: 10.1177/0333102417738202
  • 2. Crawford CC, Huynh MT, Kepple A, Jonas WB. Systematic assessment of the quality of research studies of conventional and alternative treatment(s) of primary headache. Pain Physician 2009; 12 (2): 461-470.
  • 3. World Health Organization. Guidelines on developing consumer information on proper use of traditional, complementary and alternatives medicine. Geneva, Switzerland: WHO; 2004.
  • 4. Geleneksel ve Tamamlayıcı Tıp Uygulamaları Yönetmeliği. Resmi Gazete 27.10.2014; Sayı No: 29158.
  • 5. Adams J, Barbery G, Lui CW. Complementary and alternative medicine use for headache and migraine: a critical review of the literature. Headache 2013; 53: 459-473. doi: 10.1111/j.1526- 4610.2012.02271.x
  • 6. Karakurum Göksel B, Coşkun Ö, Ucler S, Karatas M, Ozge A et al. Use of complementary and alternative medicine by a sample of Turkish primary headache patients. Agri 2014; 26 (1): 1-7. doi: 10.5505/agri.2014.04909
  • 7. Ertem DH. The association between chronicity of migraine and complementary and alternative medication use: the Turkish perspective. European Neurology 2019; 81 (1-2): 24-29. doi: 10.1159/000499910
  • 8. Bıçakçı Ş, Öztürk M, Üçler S, Karlı N, Siva A. Başağrısı Tanı ve Tedavi Güncel Yaklaşımlar. İstanbul, Turkey: Galenos Yayınevi; 2018. pp. 111-117 (in Turkish).
  • 9. Baykan B, Ertas M, Karli N, Akat-Aktas S, Uzunkaya O et al. MIRA-Neurology Study Group. The burden of headache in neurology outpatient clinics in Turkey. Pain Practice 2007; 7: 313-323. doi: 10.1111/j.1533-2500.2007.00154.x
  • 10. Lambert TD, Morrison KM, Edwards J, Clarke CE. The use of complementary and alternative medicine by patients attending a UK headache clinic. Complementary Therapies in Medicine 2010; 18 (3-4): 128-34. doi: 10.1016/j.ctim.2010.05.035
  • 11. Gaul C, Eismann R, Schmidt T, May A, Leinisch E et al. Use of complementary and alternative medicine in patients suffering from primary headache disorders. Cephalalgia 2009; 29: 1069- 1078. doi: 10.1111/j.1468-2982.2009.01841.x
  • 12. Krasenbaum LJ. A review of complementary and alternative medicine use among U.S. adults with headache or migraine: results from the 2012 National Health Interview Survey. Headache 2017; 57 (8): 1284-1285. doi: 10.1111/head.13163
  • 13. Kristoffersen ES, Aaseth K, Grande RB, Lundqvist C, Russell MB. Self-reported efficacy of complementary and alternative medicine: the Akershus study of chronic headache. The Journal of Headache and Pain 2013; 14 (1): 36. doi: 10.1186/1129-2377- 14-36
  • 14. Al-Hashel JY, Ahmed SM, Alshawaf FJ, Alroughani R. Use of traditional medicine for primary headache disorders in Kuwait. The Journal of Headache and Pain 2018; 19 (1): 118. doi: 10.1186/s10194-018-0950-3
  • 15. Wells RE, Bertisch SM, Buettner C, Phillips RS, McCarthy EP. Complementary and alternative medicine use among adults with migraines/severe headaches. Headache 2011; 51: 1087- 1097. doi: 10.1111/j.1526-4610.2011.01917.x
  • 16. Millstine D, Chen CY, Bauer B. Complementary and integrative medicine in the management of headache. British Medical Journal 2017; 357: J1805. doi: 10.1136/bmj.j1805
  • 17. Peter S, Ting W, Scrivani S, Korkin E, Okvat H et al. Survey on the use of complementary and alternative medicine among patients with headache syndromes. Cephalalgia 2002; 22: 395- 400. doi: 10.1046/j.1468-2982.2002.00376.x
  • 18. Rhee TG, Harris IM. Reasons for and perceived benefits of utilizing complementary and alternative medicine in U.S. adults with migraines/severe headaches. Complementary Therapies in Clinical Practice 2018; 30: 44-49. doi: 10.1016/j.ctcp.2017.12.003
  • 19. Rossi P, Di Lorenzo G, Faroni J, Malpezzi MG, Cesarino F et al. Use of complementary and alternative medicine by patients with chronic tension-type headache: results of a headache clinic survey. Headache 2006; 46: 622-631. doi: 10.1111/j.1526- 4610.2006.00412.x
  • 20. Linde K, Allais G, Brinkhaus B, Manheimer E, Vickers A at al. Acupuncture for tension-type headache. Cochrane Database Systematic Reviews 2009; CD007587. doi: 10.1002/14651858
  • 21. Rossi P, Di Lorenzo G, Malpezzi MG, Faroni J, Cesarino F et al. Prevalence, pattern and predictors of use of complementary and alternative medicine (CAM) in migraine patients attending a headache clinic in Italy. Cephalalgia 2005; 25: 493-506. doi: 10.1111/j.1468-2982.2005.00898.x
  • 22. Rossi P, Torelli P, Di Lorenzo C, Sances G, Manzoni GC et al. Use of complementary and alternative medicine by patients with cluster headache: Results of a multi-centre headache clinic survey. Complementary Therapies in Medicine 2008; 16: 220- 227. doi: 10.1016/j.ctim.2007.05.002
  • 23. Rhee TG, Harris IM. Gender differences in the use of complementary and alternative medicine and their association with moderate mental distress in U.S. adults with migraines/ severe headaches. Headache 2017; 57 (1): 97-108. doi: 10.1111/ head.12986
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards

Leylagül KAYNAR, Recep Civan YÜKSEL, Kürşat GÜNDOĞAN, Şahin TEMEL, Murat SUNGUR, Bülent ESER, Nilgün APLTEKİNOĞLU MENDİL

Synergistic effect of vancomycin combined with cefotaxime, imipenem, or meropenem against Staphylococcus aureus with reduced susceptibility to vancomycin

Arpasiri SRİSRATTAKARN, Chonthicha CHAİYAPOKE, Sirikarn BOONCHAROEN, Sujintana WONGTHONG, Aroonwadee CHANAWONG, Patcharaporn TİPPAYAWAT, Ratree TAVİCHAKORNTRAKOOL, Aroonlug LULİTANOND

Determinants of remission in a case series of medullary thyroid carcinoma

Tuğçe APAYDIN, Dilek YAVUZ, Eren İMRE

Folfirinox versus gemcitabine-cisplatin combination as first-line therapy in treatment of pancreaticobiliary cancer

Ahmet ÖZET, Dilek YAPAR, Hasan SATIŞ, Neslihan KAYAHAN, Mustafa KARACA

The effect of carbon monoxide releasing molecule-2 (CORM-2) on healing of ischemic colon anastomosis in rats

Uğur ERÇİN, Metin ERCAN, Erdal Birol BOSTANCI, Kadir Koray BAŞ, Ali Kemal KAYAPINAR, Seda YAMAK, Mehmet Akif TÜRKOĞLU

Mid-term results of total hip arthroplasty with subtrochanteric Z-osteotomy in Crowe type 3-4 developmental hip dysplasia

İzzet BİNGÖL, Vedat BİÇİCİ, Tamer SAZAK

Preferences of inflammatory arthritis patients for biological disease-modifying antirheumatic drugs in the first 100 days of the COVID-19 pandemic

Levent KILIÇ, Hakan EMMUNGİL, Emre BİLGİN, Timuçin KAŞİFOĞLU, Süleyman Serdar KOCA, Servet AKAR, Nilüfer KANITEZ, Cemal BES, Gezmiş KİMYON, Emel Gönüllü, Rıdvan MERCAN, Duygu ERSÖZLÜ, Umut KALYONCU, Sedat KİRAZ, Seda ÇOLAK, Orhan KÜÇÜKŞAHİN, Yavuz PEHLİVAN, Ömer KARADAĞ, Ediz DALKILIÇ, Ali İhsan ERT

Circulating miR-29c-3p is downregulated in patients with acromegaly

Kuyaş HEKİMLER ÖZTÜRK, Hakan KORKMAZ, Bora TORUS

Effectiveness of mepolizumab therapy on symptoms, asthma exacerbations, steroid dependence, and small airways in patients with severe eosinophilic asthma

Nuri TUTAR, İnsu YILMAZ, Sakine NAZİK BAHÇECİOĞLU, Murat TÜRK, Gülden PAÇACI ÇETİN, Bahar ARSLAN

Appendectomy history is associated with severe disease and colchicine resistance in adult familial Mediterranean fever patients

Nazife Şule YAŞAR BİLGE, Erdal BODAKÇİ, Timuçin KAŞİFOĞLU, Berna GÖKER, Şeminur HAZNEDAROĞLU, Mehmet AKİF ÖZTÜRK, Nuh ATAŞ, Reyhan BİLİCİ SALMAN, Abdurrahman TUFAN, Hasan SATIŞ, Hakan BABAOĞLU, Berkan ARMAĞAN, Umut KALYONCU, Alper SARI, Gözde KÜBRA YARDIMCI, Levent KILIÇ