Ahmet Bülent YAZICI, Arzu TATAR, Şenol DANE, Esra KILIÇ, Sevda YÜKSEL, Serap YILDIRIM, Serpil CANPOLAT, Erol OZAN

Sex- and diagnosis-related diff erences in nostril dominance may be associated with hemisphere dysfunction in aff ective disorders

Amaç: Aff ektif bozukluklu hastalardaki burun dominans farklılıklarını sağlıklı bireylerle karşılaştırarak ortaya koymak. Yöntem ve gereç: Çalışmaya 26 erkek ve 18 kadın bipolar I, 11 erkek ve 15 kadın unipolar depresyonlu, ve 30 erkek ve 34 kadın sağlıklı kontrol denekleri katıldı. Burun dominansı burun hava akımı ölçülerek tayin edildi. Burun hava akımı saat 08.00 ile 20.00 arası 30 dakikalık aralıklarla 24 kez ölçüldü. Bulgular: Unipolar depresyonlu hastalar anlamlı sol, bipolar I hastalar ise anlamlı sağ burun dominansına sahiptiler. Bipolarlardaki sağ ve unipolarlardaki sol dominanslarının her ikisi de kadınlık cinsiyeti ile ilişkili bulundu. Sonuç: Bu bulgular unipolar depresyonun kadınlarda nasal siklusda sol hemisfer dis- veya hipo-fonksiyonunu ima etmektedir. Buna karşılık bipolar I kadınlarda sağ hemisfer dis- veya hipo-fonksiyonu ile ilişkili olabilir.

Bipolar bozukluklarda burun dominansındaki farklar

Aim: To investigate the diff erences in nostril dominance in aff ective disordered patients in comparison with healthy subjects. Materials and methods: A total of 26 male and 18 female bipolar I disordered inpatients, 11 male and 15 female unipolar depressed inpatients, and 30 male and 34 female healthy control subjects were evaluated. Nostril dominance was assessed by measuring nostril airfl ow. Nostril airfl ow was measured 24 times, at 30-min intervals from 08.00 hours to 20.00 hours. Results: Unipolar depressed patients had signifi cantly more left nostril dominance; bipolar I disordered patients had signifi cantly more right nostril dominance. Both right nostril dominance in bipolar patients and left nostril dominance in unipolar patients were related to female sex. Conclusion: Th ese results suggest that unipolar depression might be associated with left hemisphere dysfunction or hypofunction in females, in terms of the nasal cycle. However, bipolar I disorder might be associated with right hemisphere dysfunction or hypofunction in females, in terms of the nasal cycle.

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