Mustafa YILDIRIM, Selma ÇAKIR, Mehmet Faruk GEYİK, Davut ÖZDEMİR, Ertuğrul GÜÇLÜ, Mehmet ÇAKIR

Seroprevalences and associated risk factors of hepatitis B and C in adults

Chronic hepatitis due to hepatitis B and hepatitis C virus infections is the most common cause of chronic liver disease. In this study we aimed to find out seroprevalences and associated risk factors of hepatitis B and C in adults in Düzce. Materials and methods: The sample of study was determined with a cluster-type sampling method. The study included 1321 people, consisting of 667 women and 654 men who were 18 years or older. A questionnaire about demographic information and risk factors was applied. Results: Seroprevalences of HBsAg, anti-HBs, and anti-HCV were 4.8%, 9.4%, and 0.7%, respectively. HBsAg seroprevalences were found to be statistically higher in the dental visit group (8.9% versus 4.0%, P = 0.002) and in people living within the same house with hepatitis B carriers (11.5% versus 4.6%, P = 0.036). Living in Düzce during the 1999 earthquake and staying in prefabricated houses after the earthquake were not risk factors of HBsAg carriage. Conclusion: HBsAg and anti-HCV seroprevalences in Düzce were in parallel with the previous data from Turkey and a low ratio of anti-HBs appeared. Identifying risk groups with large epidemiological screening studies and vaccination of nonimmune people are essential.

Anahtar Kelimeler:

Hepatitis B, hepatitis C, seroprevalence, risk factors, adults

Seroprevalences and associated risk factors of hepatitis B and C in adults

Keywords:

Hepatitis B, hepatitis C, seroprevalence, risk factors, adults,

PDF

___

Kaçar F, Erol S, Parlak M, Kadanalı A. Seroprevalence of hepatitis B virus infection in Erzurum. Infek Derg 2003; 17: 389–393 (in Turkish with an English abstract).
Aslan G, Ulukanlıgil M, Seyrek A. Şanlıurfa’da HBsAg, Anti- HBs ve Anti HCV seroprevalansı. Viral Hepatit Derg 2001; 7: 408–410 (in Turkish).
Banak S, Yoldaşcan E, Kılıç B. The prevalence of hepatitis B surface antigen (HBsAg) and anti-hepatitis C virus (anti-HCV) in subjects of age ten and over in the semirural areas of Adana and factors affecting the prevalence. Infek Derg 2002; 16: 133– 140 (in Turkish with an English abstract).
Kaçmaz B. Seroprevalence of hepatitis B and hepatitis C infections in Ankara city. Viral Hepatit Derg 2003; 8: 97–101 (in Turkish with an English abstract).
Aşan A, Açar S, Çatak B, Karahasanoğlu FB, Turgut H. Evaluation of hepatitis B seroprevalence of Denizli city. Viral Hepatit Derg 2007; 12: 40–48 (in Turkish with an English abstract).
Karabay O, Serin E, Tamer A, Gökdoğan F, Alpteker H, Ozcan A, Gündüz H. Hepatitis B carriage and Brucella seroprevalence in urban and rural areas of Bolu province of Turkey: a prospective epidemiologic study. Turk J Gastroenterol 2004; 15: 11–13.
Delialioğlu N, Öztürk C, Aslan G. Seroprevalence of HBsAg, anti-HBs, anti-HCV and anti-HDV in Mersin. Viral Hepatit Derg 2001; 7: 416–418 (in Turkish with an English abstract).
Dursun M, Ertem M, Yılmaz Ş, Saka G, Özekinci T, Şimşek Z. Prevalence of hepatitis B infection in the southeastern region of Turkey: comparison of risk factors for HBV infection in rural and urban areas. Jpn J Infect Dis 2005; 58: 15–19.
Yalçın D, Yeler H, Tufan N, Gedik R. Sivas C.Ü. Diş Hekimliği Fakültesine başvuran hastalarda Hepatit B, Hepatit C sıklığının saptanması. CÜ Diş Hek Fak Derg 2001; 4: 97–101 (in Turkish with an English abstract).
Doğru Ü. Nozokomiyal viral infeksiyonlardan korunma.. Klimik Derg 2000; 33: 32–34 (in Turkish).
Khan H, Hayat Z, Rehman SU, Zarif M. Comparative analysis of risk factors and complications of hepatitis B and C infections at Khyber Teaching Hospital, Peshawar. Hepat Mon 2007; 7: 83–86.
Sali S, Bashtar R, Alavian SM. Risk Factors in chronic hepatitis B infection: a case-control study. Hepat Mon 2005; 5: 109–115.
Erden S, Büyüköztürk S, Çalangu S, Kardeş BA, Kaysı A, Yılmaz G, Badur S, Palandüz Ş. Seroprevalences of HBsAg, anti-HBs, and anti-HCV in out patients. Türk Mikrobiyol Cem Derg 2000; 30: 131–134 (in Turkish with an abstract in English).
Wang CS, Chang TT, Yao WJ, Chou P. Comparison of hepatitis B virus and hepatitis C virus prevalence and risk factors in a community-based study. Am J Trop Med Hyg 2002; 66: 389– 393.
Yenice N, Cansız M, Arıcan N, Gökten Y, Durgut C, Türkmen S. HBsAg and anti-HCV seroprevalence in spouses of patients with chronic hepatitis B and chronic hepatitis C. Akademik Gastroenterol Dergisi 2004; 3: 79–82 (in Turkish with an English abstract).
Nurgalieva ZZ, Hollinger FB, Graham DY, Zhangabylova S, Zhangabylov A. Epidemiology and transmission of hepatitis B and C viruses in Kazakhstan. World J Gastroenterol 2007; 13: 1204–1207.
Otkun M, Erdoğan MS, Tatman M, Akata F. Exposure time to hepatitis B virus and associated risk factors among children in Edirne, Turkey. Epidemiol Infect 2005; 133: 509–516.
Khan S, Rai MA, Khan A, Farooqui A, Kazmi SU, Ali SH. Prevalence of HCV and HIV infections in 2005 earthquake- affected areas of Pakistan. BMC Infect Dis 2008; 8: 147.
Badur S. Hepatitis B infections: epidemiology and vaccine. Klinik Gelişim 2005; 18: 32–43 (in Turkish with an abstract in English).
Sunanchaikarn S, Theamboonlers A, Chongsrisawat V, Yoocharoen P, Tharmaphornpilas P, Warinsathien P, Sinlaparatsamee S, Paupunwatana S, Chaiear K, Khwanjaipanich S et al. Seroepidemiology and genotypes of hepatitis C virus in Thailand. Asian Pac J Allergy Immunol 2007; 25: 175–182.
Mishra S, Chayani N, Sarangi G, Mallick B, Pati SB. Seroprevalence of anti HCV antibody in and around Cuttack, Orissa. Indian J Med Microbiol 2002; 20: 40–41.
Kölgeliler S, Ertek M, Erol S, Taşyaran MA. Hepatit C virus seroprevalence central and rural areas of Erzurum. Viral Hepatit Derg 2003; 8: 166–170 (in Turkish with an English abstract).
Ağuş N, Özkalay Yılmaz N, Cengiz A, Şanal E, Sert H. HBsAg, anti-HCV and anti-HIV seroprevalence in blood donors. ANKEM 2008; 22: 7–9 (in Turkish with an English abstract).
Kökoğlu ÖF, Geyik MF, Uçmak H, Aslan S, Ayaz C, Hoşoğlu S. The prevalence of HBsAg and anti-HCV in blood donors at Diyarbakır region. Viral Hepatit Derg 2003; 8: 56–59 (in Turkish with abstract in English).