Seroprevalence of Hepatitis A Infection in the Turkish Republic of Northern Cyprus

Aims: This study was conducted to determine the seroprevalence of hepatitis A virus (HAV) infection in the Turkish Republic of Northern Cyprus. Materials and Methods: A total of 660 unvaccinated persons 1 to 30 years old were selected for the study with cluster sampling. Information on sociodemographic characteristics was gathered for each participant and, in 641 of them, anti-HAV antibodies were assayed using an enzyme immune assay. Results: Anti-HAV prevalence in the Turkish population under the age of 30 in Northern Cyprus was 23.9%. For the age groups 1-5, 6-10 and 11-15 years, seroprevalence rates were relatively low (11.4, 9.4 and 12%, respectively). For age groups 16 years and over, HAV seroprevalence gradually increased with age, rising to 30.4% in 16 to 20 years and to 52.5% in 21 to 30 years of age. In addition to age, other variables significantly associated with HAV seroprevalence included low family income, family size, waste water sewage, and the education level of parents. Conclusions: Anti-HAV seroprevalence in the Turkish Republic of Northern Cyprus shows an intermediate prevalence. As well as expanding health education and improving sanitation, a hepatitis A universal mass vaccination program would be logical for the population.

Seroprevalence of Hepatitis A Infection in the Turkish Republic of Northern Cyprus

Aims: This study was conducted to determine the seroprevalence of hepatitis A virus (HAV) infection in the Turkish Republic of Northern Cyprus. Materials and Methods: A total of 660 unvaccinated persons 1 to 30 years old were selected for the study with cluster sampling. Information on sociodemographic characteristics was gathered for each participant and, in 641 of them, anti-HAV antibodies were assayed using an enzyme immune assay. Results: Anti-HAV prevalence in the Turkish population under the age of 30 in Northern Cyprus was 23.9%. For the age groups 1-5, 6-10 and 11-15 years, seroprevalence rates were relatively low (11.4, 9.4 and 12%, respectively). For age groups 16 years and over, HAV seroprevalence gradually increased with age, rising to 30.4% in 16 to 20 years and to 52.5% in 21 to 30 years of age. In addition to age, other variables significantly associated with HAV seroprevalence included low family income, family size, waste water sewage, and the education level of parents. Conclusions: Anti-HAV seroprevalence in the Turkish Republic of Northern Cyprus shows an intermediate prevalence. As well as expanding health education and improving sanitation, a hepatitis A universal mass vaccination program would be logical for the population.

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  • Erdogan MS, Oktun M, Tatman-Oktun M, Akata F, Türe M. The epidemiology of hepatitis a virus infection in children, in Edirne, Turkey. Eur J Epidemiol 2004; 19: 267-73.
  • Mossong J, Putz L, Patiny S, Schneider F. Seroepidemiology of hepatitis A and hepatitis B virus in Luxembourg. Epidemiol Infect ; 134: 808-13. Beran J, Douda P, Rychly R. Seroprevalence of viral hepatitis A in the Czech Republic. Eur J Epidemiol 1999; 15: 805-8.
  • Termorshuizen F, Dorigo-Zetsma JW, de Melker HE, van den Hof S, Conyn-Van Spaendonck MA. The prevalence of antibodies to hepatitis A virus and its determinants in The Netherlands: a population-based survey. Epidemiol Infect 2000; 124: 459-66.
  • Bell BP, Kruszon-Moran D, Shapiro CN, Lambert SB, McQuillan GM, Margolis HS. Hepatitis A virus infection in the United States: serologic results from the Third National Health and Nutrition Examination Survey. Vaccine 2005; 23: 5798-806.
  • Letaief A, Kaabia N, Gaha R, Bousaadia A, Lazrag F, Trabelsi H et al. Age-specific seroprevalence of hepatitis a among school children in central Tunisia. Am J Trop Med Hyg 2005; 73: 40-3. de silva KS, Weerasuriya DC, Peelawattage M, Fernando S.
  • Seroprevalence of hepatitis A antibodies in relation to social factors--a preliminary study. Ceylon Med J 2005; 50: 54-8.
  • Mall ML, Rai RR, Philip M, Naik G, Parekh P, Bhawnani SC et al. Seroepidemiology of hepatitis A infection in India: changing pattern. Indian J Gastroenterol 2001; 20: 132-5.
  • Mehr AJ, Ardakani MJ, Hedayati M, Shahraz S, Mehr EJ, Zali MR. Age-specific seroprevalence of hepatitis A infection among children visited in pediatric hospitals of Tehran, Iran. Eur J Epidemiol 2004; 19: 275-8.
  • Lin JB, Lin DB, Chen SC, Chen PS, Chen WK. Seroepidemiology of hepatitis A, B, C, and E viruses infection among preschool children in Taiwan. J Med Virol 2006; 78: 18-23.
  • Fix AD, Martin OS, Gallicchiol L, Vial PA, Lagos R. Age specific prevalence of antibodies to hepatitis A in Santiago, Chile: risk factors and shift in age of infection among children and young adults. Am J Trop Med Hyg 2002; 66: 628-32.
  • Tanaka J. Hepatitis A shifting epidemiology in Latin America. Vaccine 2000; 18 (Suppl 1): 57-60.
  • Anis E, Leventhal A, Roitman M, Slater PE. Introduction of routine hepatitis A immunization in Israel--the first in the world. Harefuah 2000; 138: 177-80.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
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