Naime CANORUÇ, Mehmet DURSUN, Aytaç ATAMER, Fikri CANORUÇ, Ramazan ÇİÇEK, Cengiz TURGUT, Ensari GÜNELİ

7490

Protective Effects of Vitamin E Selenium and Allopurinol Against Stress-induced Ulcer Formation in Rats

This study was carried out in the Health Research Center (DÜSAM) laboratory of Dicle University. Vitamin E, Selenium and Allopurinol were given to counteract gastric damage caused by stress in rats. In the study 64 male Sprague dawley rats were used. They were divided into 8 groups, and protective agents were applied at different doses for 8 weeks. Then, performing cold-restraint stress stomach tissues were taken out and investigated macroscopically to determine mucosal damage. Lipid peroxidation levels in the stomach specimens were determined by identifying Malondialdehyde (MDA) levels by the thiobarbituric acid method. These agents have shown protective effects against cold-restraint stress. Evaluating macroscopic examinations of stomach specimens and considering MDA levels determined this. The results obtained from the Vit-E (10 mg/kg/day), Allopurinol and Selenium groups were found to be statistically significant when compared to the control group (p
Anahtar Kelimeler:

Vit-E, Selenium, Allopurinol and Stress-induced ulcer

Protective Effects of Vitamin E Selenium and Allopurinol Against Stress-induced Ulcer Formation in Rats

This study was carried out in the Health Research Center (DÜSAM) laboratory of Dicle University. Vitamin E, Selenium and Allopurinol were given to counteract gastric damage caused by stress in rats. In the study 64 male Sprague dawley rats were used. They were divided into 8 groups, and protective agents were applied at different doses for 8 weeks. Then, performing cold-restraint stress stomach tissues were taken out and investigated macroscopically to determine mucosal damage. Lipid peroxidation levels in the stomach specimens were determined by identifying Malondialdehyde (MDA) levels by the thiobarbituric acid method. These agents have shown protective effects against cold-restraint stress. Evaluating macroscopic examinations of stomach specimens and considering MDA levels determined this. The results obtained from the Vit-E (10 mg/kg/day), Allopurinol and Selenium groups were found to be statistically significant when compared to the control group (p
Keywords:

Vit-E, Selenium, Allopurinol and Stress-induced ulcer,

PDF
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Arşiv
Sayıdaki Diğer Makaleler

Cytomorphologic Analysis of Papanicolaou Stained Smears Collected from Floor of the Mouth Mucosa in Patients with or without Oral Malignancy

Nur MOLLAOĞLU, Jonathan George COWPE, Rita WALKER

The histopathologic and the immunohistochemical features of secretory meningiomas

M. Şerefettin CANDA, Merih GÜRAY, Ümit D. ACAR

Production of Monoclonal Antibody Specific for Human Hemoglobin

Selma ÖZTÜRK, Beyazıt ÇIRAKOĞLU

Diabetic Osteopathy: Who is at Risk?

Serap DEMİR, Selma KARAAHMETOĞLU, Ayşin ÖĞE, Seniha NALDÖKEN, Osman MÜFTÜOĞLU

In Vitro Mic Determination of Haemophilus Influenzae Strains Using E-Test

Nilay ÇÖPLÜ, Engin GÜVENER, Selda ULUUTKU, Orhan Cem AKTEPE

Apolipoprotein-E Genotyping in Patients with Coronary Heart Disease

İbrahim PİRİM, Ersin AKARSU, Fevzi POLAT, Engin BOZKURT, Yaşar Nuri ŞAHİN

The Effects of Benzo(A) Pyrene Doxorubicin and Paclitaxel on P170 Glycoprotein

Didem COŞAN, Ayşe BAŞARAN

Is Eradication of Helicobacter pylori an Alternative Treatment for Rosacea?

Yüksel Pınar BAŞAK, Cicioğlu Buket ARIDOĞAN

Flow Cytometric Analysis of the Effects of Methotrexate and Vepesid on the HEp-2 Cell Cycle

Salih. ÇETİNER, Nizami DURAN, Adil M. ALLAHVERDİYEV

A father born to consanguineous parents had double translocation 21;22 [44,XY, t(21q;22q), t(21q;22q)] due to familial translocation in four generations

Tufan ÇANKAYA, Cumhur GÜNDÜZ, Gül SAPMAZ, Cihangir ÖZKINAY, Özgür ÇOĞULU, Ferda ÖZKINAY