Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience

Öz The HIV-infected population is aging, and the concomitant comorbidities increase the likelihood of polypharmacy. There is a scarcity of data for determining drug-related problems in people living with HIV/AIDS (PLWHA). Materials and methods: This cross-sectional study was carried out between 1 September 2015 and 1 July 2016. All patients underwent a face-to-face interview with a clinical pharmacist. PCNE Classification V 7.0 was used classify incident drug-related problems (DRPs). Results: The mean age of the patients was 40.4 ± 13.06 years. The rate of polypharmacy was 66.1% in patients with comorbidities and 12.3% in those without comorbidities (P < 0.001). DRPs were more prominent in older patients (46 vs. 37 years, P < 0.001), those with longer durations of antiretroviral therapy (ART) (45 vs. 27 months, P = 0.014), and those with lower education levels (P = 0.013). Receiving >3 ART drugs was associated with more DRPs in the logistic regression model (odds ratio: 8.299, 95% confidence interval: 1.924-35.803). Fifty-eight interventions were performed in 45 (24.9%) patients. Clinical pharmacist interventions were performed in 18.9% of patients without polypharmacy and in 38.9% of patients with polypharmacy (P < 0.001). Conclusion: DRPs and polypharmacy are common among elderly PLWHA. More interventions are warranted to boost the quality of life in aging PLWHA.

Kaynak Göster

Bibtex @ { tbtkmedical577802, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2019}, volume = {49}, pages = {222 - 229}, doi = {}, title = {Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience}, key = {cite}, author = {Kara, Emre and İnkaya, Ahmet Çağkan and Haklı, Duygu Aydin and Demırkan, Salih Kutay and Ünal, Serhat} }
APA Kara, E , İnkaya, A , Haklı, D , Demırkan, S , Ünal, S . (2019). Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience . Turkish Journal of Medical Sciences , 49 (1) , 222-229 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45750/577802
MLA Kara, E , İnkaya, A , Haklı, D , Demırkan, S , Ünal, S . "Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience" . Turkish Journal of Medical Sciences 49 (2019 ): 222-229 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45750/577802>
Chicago Kara, E , İnkaya, A , Haklı, D , Demırkan, S , Ünal, S . "Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience". Turkish Journal of Medical Sciences 49 (2019 ): 222-229
RIS TY - JOUR T1 - Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience AU - Emre Kara , Ahmet Çağkan İnkaya , Duygu Aydin Haklı , Salih Kutay Demırkan , Serhat Ünal Y1 - 2019 PY - 2019 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 222 EP - 229 VL - 49 IS - 1 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience %A Emre Kara , Ahmet Çağkan İnkaya , Duygu Aydin Haklı , Salih Kutay Demırkan , Serhat Ünal %T Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience %D 2019 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 49 %N 1 %R %U
ISNAD Kara, Emre , İnkaya, Ahmet Çağkan , Haklı, Duygu Aydin , Demırkan, Salih Kutay , Ünal, Serhat . "Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience". Turkish Journal of Medical Sciences 49 / 1 (Şubat 2019): 222-229 .
AMA Kara E , İnkaya A , Haklı D , Demırkan S , Ünal S . Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience. Turkish Journal of Medical Sciences. 2019; 49(1): 222-229.
Vancouver Kara E , İnkaya A , Haklı D , Demırkan S , Ünal S . Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience. Turkish Journal of Medical Sciences. 2019; 49(1): 222-229.
IEEE E. Kara , A. İnkaya , D. Haklı , S. Demırkan ve S. Ünal , "Polypharmacy and drug-related problems among people living with HIV/AIDS: a single-center experience", Turkish Journal of Medical Sciences, c. 49, sayı. 1, ss. 222-229, Şub. 2019

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