Aim: In this study, we aimed to investigate the effect of in-and-out urethral catheterization on serum total and free prostate specific antigen (PSA) levels and free/total PSA ratio. Materials and Methods: This is a prospective study including 24 patients who admitted with lower urinary tract symptoms and underwent in-and-out urethral catheterization with 18 F Foley catheter inserted for postvoiding residual urine measurement. Blood samples were withdrawn to determine serum total and free PSA levels and free/total PSA ratio immediately before, and at 1, 24 and 72 hours after urethral catheterization. Results: There was no alteration in total and free PSA levels or and free/total PSA ratio due to in-and-out urethral catheterization in patients who underwent postvoiding residual urine measurement (ptotal PSA=0.536, pfree PSA=0.099, pfree/total PSA=0.497). Conclusions: In our study, in-and-out urethral catheterization was not found to be an effective factor on serum total and free PSA levels or free/total PSA ratio.

Aim: In this study, we aimed to investigate the effect of in-and-out urethral catheterization on serum total and free prostate specific antigen (PSA) levels and free/total PSA ratio. Materials and Methods: This is a prospective study including 24 patients who admitted with lower urinary tract symptoms and underwent in-and-out urethral catheterization with 18 F Foley catheter inserted for postvoiding residual urine measurement. Blood samples were withdrawn to determine serum total and free PSA levels and free/total PSA ratio immediately before, and at 1, 24 and 72 hours after urethral catheterization. Results: There was no alteration in total and free PSA levels or and free/total PSA ratio due to in-and-out urethral catheterization in patients who underwent postvoiding residual urine measurement (ptotal PSA=0.536, pfree PSA=0.099, pfree/total PSA=0.497). Conclusions: In our study, in-and-out urethral catheterization was not found to be an effective factor on serum total and free PSA levels or free/total PSA ratio.