Health-related quality of life of pediatric renal transplant recipientsand their parents: the role of associated factors and clinical counseling

Health-related quality of life of pediatric renal transplant recipientsand their parents: the role of associated factors and clinical counseling

Background/aim: This study evaluates the health-related quality of life (HRQoL) of pediatric renal transplant recipients and their parents and investigates the effects of clinical, socioeconomic, and psychological factors as well as continuous counseling on the HRQoL. Materials and methods: Patients aged 8 17 years (mean: 14.9 ± 2.9) were enrolled. Clinical and demographic data were noted. The Beck Depression Inventory (BDI), Rosenberg Self-Esteem Scale (RSES), and Turkish version of the Kinder Lebensqualität Fragebogen (KINDL) questionnaire for children and the BDI, RSES, parent-proxy version of KINDL, and Short-Form 36 (SF-36) for parents were applied (step 1). Following a 1-year counseling program, the tests were repeated (step 2). Results: Child-self and parent-proxy KINDL scores were optimal with no difference between periods (for child-self and parent-proxy scores, P > 0.05). Parent SF-36 scores indicated optimal results. Parent RSES scores decreased in step 2 (P < 0.05). The BDI scores were higher in parents than children in both periods (P < 0.05 for step 1 and P < 0.01 for step 2). Higher creatinine levels, lower monthly income, and urological comorbidities modified the HRQoL negatively in step 1. Conclusion: Continuous education with psychosocial counseling carries importance in improving HRQoL in the posttransplant perio

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  • 1. Falger J, Landolt MA, Latal B, Rüth EM, Neuhaus TJ, Laube GF. Outcome after renal transplantation. Part II: quality of life and psychosocial adjustment. Pediatr Nephrol 2008; 23: 1347-1354.
  • 2. Dobbels F, van Damme-Lombaert R, Vanhaecke J, de Geest S. Growing pains: non-adherence with the immunosuppressive regimen in adolescent transplant recipients. Pediatr Transplant 2005: 9: 381-390.
  • 3. Qvist E, Narhi V, Apajasalo M, Rönnholm K, Jalanko H, Almqvist F, Holmberg C. Psychosocial adjustment and quality of life after renal transplantation in early childhood. Pediatr Transplant 2004; 8: 120-125.
  • 4. Goldstein SL, Graham N, Warady BA, Seikaly M, McDonald R, Burwinkle TM, Limbers CA, Varni JW. Measuring healthrelated quality of life in children with ESRD: performance of the generic and ESRD-specific instrument of the Pediatric Quality of Life Inventory (PedsQL). Am J Kidney Dis 2008; 51: 285-297.
  • 5. Sandarac SS Landgraf JM, Neighbors K, Cohn RA, Alonso EM. Adolescent health-related quality of life following liver and kidney transplantation. Am J Transplant 2007; 7: 982-989.
  • 6. Hamiwka LA, Cantell M, Crawford S, Clark CG. Physical activity and health related quality of life in children following kidney transplantation. Pediatr Transplant 2009; 13: 861-867.
  • 7. Manificat S, Dazord A, Cochat P, Morin D, Plainquet F, Debray D. Quality of life of children and adolescents after kidney or liver transplantation: child, parents and caregiver’s point of view. Pediatr Transplant 2003; 7: 228-235.
  • 8. Anthony SJ, Hebert D, Todd L, Korus M, Langlois V, Pool R, Robinson LA, Williams A, Pollock-Barziv SM. Child and parental perspectives of multidimensional quality of life outcomes after kidney transplantation. Pediatr Transplant 2010; 14: 249-256.
  • 9. Hasegawa A, Oshima S, Takahashi K, Uchida K, Ito K, Sonoda T. Improvement of quality of life in tacrolimus-based pediatric renal transplant recipients and their caregivers, including donors. Transplant Proc 2005; 37: 1771-1773.
  • 10. Diseth TH, Tangeraas T, Reinfjell T, Bjerre A. Kidney transplantation in childhood: mental health and quality of life of children and caregivers. Pediatr Nephrol 2011; 26: 1881- 1892.
  • 11. Buyan N, Türkmen MA, Bilge I, Baskin E, Haberal M, Bilginer Y, Mir S, Emre S, Akman S, Ozkaya O et al. Quality of life in children with chronic kidney disease (with child and parent assessments). Pediatr Nephrol 2010; 25: 1487-1496.
  • 12. Akchurin OM, Melamed ML, Hashim BL, Kaskel FJ, Del Rio M. Medication adherence in the transition of adolescent kidney transplant recipients to the adult care. Pediatr Transplant 2014; 18: 538-548.
  • 13. Suhling H, Rademacher J, Zinowsky I, Fuge J, Greer M, Warnecke G, Smits JM, Bertram A, Haverich A, Welte T et al. Conventional vs. tablet computer-based patient education following lung transplantation--a randomized controlled trial. PLoS One 2014; 9: e90828.
  • 14. Devine KA, Reed-Knight B, Loiselle KA, Simons LE, Mee LL, Blount RL. Predictors of long-term health-related quality of life in adolescent solid organ transplant recipients. J Pediatr Psychol 2011; 36: 891-901.
  • 15. Hamel AE, Zaitsoff SL, Taylor A, Menna R, Le Grange D. Body-related social comparison and disordered eating among adolescent females with an eating disorder, depressive disorder, and healthy controls. Nutrients 2012; 4: 1260-1272.
  • 16. Kholasehzadeh G, Shiryazdi S, Neamatzadeh H, Ahmadi N. Depression levels among mothers of children with leukemia. Iran J Ped Hematol Oncol 2014; 4: 109-113.
  • 17. Bozkurt Zincir S, Sunbul M, Zincir S, Aydin Sunbul E, Oguz M, Feriha Cengiz F, Durmus E, Kivrak T, Sari I. Burden and depressive symptoms associated with adult-child caregiving for individuals with heart failure. ScientificWorldJournal 2014; 2014: 641817.
  • 18. Toker T, Tiryaki A, Özçürümez G, İskender B. The relationship between traumatic childhood experiences and proclivities towards substance abuse, self-esteem and coping strategies. Turk Psikiyatri Derg 2011; 22: 83-92.
  • 19. Erhart M, Ellert U, Kurth BM, Ravens-Sieberer U. Measuring adolescents’ HRQoL via self reports and parent proxy reports: an evaluation of the psychometric properties of both versions of the KINDL-R instrument. Health Qual Life Outcomes 2009; 7: 77.
  • 20. Jaquet A, Garanet F, Balestre E, Ekouevi DK, Azani JC, Bognounou R, Dah E, Kondombo JC, Dabis F, Drabo J. Antiretroviral treatment and quality of life in Africans living with HIV: 12-month follow-up in Burkina Faso. J Int AIDS Soc 2013; 16: 18867.
  • 21. Wiedebusch S, Konrad M, Foppe H, Reichwald-Klugger E, Schaefer F, Schreiber V, Muthny FA. Health-related quality of life, psychosocial strains, and coping in parents of children with chronic renal failure. Pediatr Nephrol 2010; 25: 1477- 1485.
  • 22. Malekahmadi MR, Rahimzadeh S, Dezfuli Nejad ML, Lankarani MM, Einollahi B, Assari S. Importance of socioeconomic, clinical, and psychological factors on healthrelated quality of life in adolescents after kidney transplant. Exp Clin Transplant 2011; 9: 50-55.
  • 23. Neu AM. Special issues in pediatric kidney transplantation. Adv Chronic Kidney Dis 2006; 13: 62-69.