Rafiye ÇİFTÇİLER, Ahmet KOLUMAN, İbrahim Celalettin HAZNEDAROĞLU, Nejat AKAR

Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance

Öz Background/aim: Ankaferd hemostat (ABS; Ankaferd blood stopper, İstanbul, Turkey) is a folkloric medicinal plant extract. The aim of this study was to determine the effect of Ankaferd hemostat (ABS) on the fate of Helicobacter pylori strains. The study also aims to determine alterations in the antimicrobial resistance of three different H. pylori strains in response to ABS exposure.Materials and methods: H. pylori Strain 1 was obtained from the culture collection ATCC 43504 and passaged three times for viability. Strain 2 was isolated from a gastric ulcer patient and Strain 3 was isolated from a gastritis patient. 1% of ABS was added to all of the strains and antimicrobial susceptibility was observed on 30 and 60 min after application.Results: The efficacy of ABS solutions in achieving significant logarithmic reduction in foodborne pathogens of H. pylori was observed in this study. This study showed that ABS has antibacterial (Anti-H. pylori) effects. Conclusion: Our present study indicated, for the first time, that ABS could act against H. pylori. ABS is clinically used for the management of GI bleeding due to benign and malignant GI lesions. Thus, the possible anti-H. pylori effect of ABS shall expand the therapeutic spectrum of the drug in GI lesions in relation to H. pylori infection such as peptic ulser disease (PUD) and lymphoid tissue (MALT) lymphomagenesis.

Anahtar Kelimeler:

Ankaferd blood stopper, gastrointestinal bleeding, Helicobacter pylori

Tam Metin

Kaynak Göster

Bibtex	`@ { tbtkmedical577825, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2019}, volume = {49}, pages = {347 - 355}, doi = {}, title = {Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance}, key = {cite}, author = {Çiftçiler, Rafiye and Koluman, Ahmet and Haznedaroğlu, İbrahim Celalettin and Akar, Nejat} }`
APA	Çiftçiler, R , Koluman, A , Haznedaroğlu, İ , Akar, N . (2019). Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance . Turkish Journal of Medical Sciences , 49 (1) , 347-355 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45750/577825
MLA	Çiftçiler, R , Koluman, A , Haznedaroğlu, İ , Akar, N . "Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance" . Turkish Journal of Medical Sciences 49 (2019 ): 347-355 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45750/577825>
Chicago	Çiftçiler, R , Koluman, A , Haznedaroğlu, İ , Akar, N . "Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance". Turkish Journal of Medical Sciences 49 (2019 ): 347-355
RIS	TY - JOUR T1 - Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance AU - Rafiye Çiftçiler , Ahmet Koluman , İbrahim Celalettin Haznedaroğlu , Nejat Akar Y1 - 2019 PY - 2019 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 347 EP - 355 VL - 49 IS - 1 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote	%0 Turkish Journal of Medical Sciences Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance %A Rafiye Çiftçiler , Ahmet Koluman , İbrahim Celalettin Haznedaroğlu , Nejat Akar %T Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance %D 2019 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 49 %N 1 %R %U
ISNAD	Çiftçiler, Rafiye , Koluman, Ahmet , Haznedaroğlu, İbrahim Celalettin , Akar, Nejat . "Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance". Turkish Journal of Medical Sciences 49 / 1 (Şubat 2019): 347-355 .
AMA	Çiftçiler R , Koluman A , Haznedaroğlu İ , Akar N . Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance. Turkish Journal of Medical Sciences. 2019; 49(1): 347-355.
Vancouver	Çiftçiler R , Koluman A , Haznedaroğlu İ , Akar N . Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance. Turkish Journal of Medical Sciences. 2019; 49(1): 347-355.
IEEE	R. Çiftçiler , A. Koluman , İ. Haznedaroğlu ve N. Akar , "Effects of Ankaferd Hemostat on Helicobacter pylori strains and antibiotic resistance", Turkish Journal of Medical Sciences, c. 49, sayı. 1, ss. 347-355, Şub. 2019