Effect of Dehydration on the Pharmacokinetics of Mefenamic Acid

The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits. High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples. The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P

Effect of Dehydration on the Pharmacokinetics of Mefenamic Acid

The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits. High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples. The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: 6
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

The Dermatophytic Flora Ratio of Dermatophytes

Hüseyin TANIŞ, Zülal AŞÇI, Gürbüz AKSOY

Cytogenetic and phenotypic findings in Turkish patients with Fanconi's anemia

Hatice ILGIN, Ayşe Nurten AKARSU, Fatma Işık BÖKESOY

The Effect of Race on the Exposure of the Internal Auditory Canal Via the Retrosigmoid Approach in Turkish Subjects

Enis Alpin GÜNERİ, Kerim CERYAN, Handan ÇAKMAKÇI, Ahmet Ömer İKİZ

MAO Inhibitors in Aging: Can They Serve as Protective Agents in Cardiac Tissue Against Oxidative Stress?

Külahçıoğlu Ferhan GİRGİN, Biltan ERSÖZ, Mert ÖZGÖNÜL, Gülriz MENTEŞ, Gülinnaz ALPER, Eser Yıldırım SÖZMEN

Effect of Exercise on Blood Antioxidant Status and Erythrocyte Lipid Peroxidation: Role of Dietary Supplementation of Vitamin E

Cemil TÜMER, Abdurrahman ŞERMET, Hüda DİKEN, Mukadder ATMACA, Mustafa KELLE

Administration of Granulocyte Colony Stimulating Factor (G-CSF) in Experimentally Infected Rats

Ömer CEVİT, Gökhan KÖYLÜOĞLU, Asım GÜLTEKİN, Fatoş TANZER, Dilara İÇAĞASIOĞLU, Ruhiye CEVİT

Prevalence of Diabetic Nephropathy in Turkish Children with Insulin-Dependent Diabetes Mellitus

Ayşenur ÖKTEN, Yusuf GEDİK, Muhterem ÖZDEMİR, Gülay KARAGÜZEL, Gülay KAYA

Cytogenetic and Phenotypic Findings in Turkish Patients With Fanconi's Anemia

Hatice ILGIN

Rh Subgroups and Kell Antigens in Patients With Thalassemia and in Donors in Turkey

Duran CANATAN, Nilgün ACAR, Banu KILIÇ

Comparative Genomic Hybridization (CGH) in Cancer Research

İbrahim KESER