Serkan YILMAZ, Melih YÜKSEL, Aslı Gülfer KARTAL, Elif YAKA, Murat PEKDEMİR

Diagnostic accuracy of noninvasive end-tidal carbon dioxide measurement in emergency department patients with suspected pulmonary embolism

Background/aim: Pulmonary embolism (PE) is a frequent health problem representing a diagnostic challenge with high mortality and morbidity rates. The aim of this study was to investigate the value of end-tidal carbon dioxide (ETCO2 ) and alveolar dead space fraction (ADSF) in the diagnosis of PE. Materials and methods: ETCO2 levels of patients with suspected PE were measured with a noninvasive mainstream sensor. ADSF of patients was calculated and PaCO2levels were also obtained. ROC curve analysis was used to determine diagnostic values of ETCO2 and ADSF for PE. Results: The study included 159 patients. The mean values for ETCO2 and ADSF were 16.27 (95% CI, 14.52 18.03) and 0.48 (95% CI, 0.43 0.539) in the PE group and 21.57 (95% CI, 20.52 22.639) and 0.35 (95% CI, 0.32 0.38) in the non-PE group. The area under the curve (AUC) and the cut-off point for ETCO2 were found as 0.751 and ≤19, with 83.8% sensitivity and 61.5% specificity. AUC and cut-off point for ADSF were found as 0.738 and >0.443, with 67.57% sensitivity and 73.77% specificity. Conclusion: The diagnostic value of calculated ADSF and noninvasive bedside ETCO2for PE was found to be low

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