Dermoscopic aspect of verrucous epidermal nevi: new findings

Background/aim: Verrucous epidermal nevi are cutaneous hamartomas with many clinical variants. Dermoscopic features ofverrucous epidermal nevus have rarely been investigated. We aimed to identify dermoscopic findings of the entity which will facilitatethe diagnostic process by reducing the use of invasive diagnostic methods.Materials and methods: The study included the patients with histopathologically approved verrucous epidermal nevus. Clinical,dermoscopic, and histopathological features of the patients were retrospectively reviewed and the findings identified were recorded.Dermoscopic examination was performed with a polarized-light handheld dermoscope with 10-fold magnification.Results: The most common dermoscopic features were thick brown circles, thick brown branched lines, and terminal hairs. The mostcommon vessel pattern was dotted vessels. Branched thick brown lines, brown globules, brown dots forming lines, serpiginous browndots, white and brown exophytic papillary structures, fine scale, thick adherent scale, and cerebriform structures were the other findings.Conclusion: We observed many vascular and nonvascular dermoscopic findings which were not described previously for the entity.Dermoscopic examination of the verrucous epidermal nevi may lead to more reliable clinical interpretation and thus may reduce theneed for histopathological investigation.

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1. Thomas VD, Swanson NA, Lee KK. Benign epithelial tumors, hamartomas, and hyperplasias. In: Wolff K, Goldsmith LA, Katz SI, et al., editors. Fitzpatrick’s Dermatology in General Medicine. 7th ed. New York, NY, USA: McGraw-Hill; 2008 pp. 1054-1067.
2. Carbotti M, Coppola R, Graziano A, Verona Rinati M, Paolilli FL et al. Dermoscopy of verrucous epidermal nevus: large brown circles as a novel feature for diagnosis. International Journal of Dermatology 2016; 55: 653-656.
3. Sugarman JL. Epidermal nevus syndromes. Seminars in Cutaneous Medicine and Surgery 2007; 26: 221-230.
4. Vujevich JJ, Mancini AJ. The epidermal nevus syndromes: multisystem disorders. Journal of the American Academy of Dermatology 2004; 50: 957-961.
5. Neri I, Savoia F, Giacomini F, Raone B, Aprile S et al. Usefulness of dermatoscopy for the early diagnosis of sebaceous nevus and differentiation from aplasia cutis congenita. Clinical and Experimental Dermatology 2009; 34: 50-52.
6. Kim NH, Zell DS, Kolm I, Oliviero M, Rabinovitz HS. The dermoscopic differential diagnosis of yellow lobular like structures. Archives of Dermatology 2008; 144: 962.
7. Okada J, Moroi Y, Tsujita J, Takahara M, Urabe K et al. Hair follicle nevus – a dermoscopic approach. European Journal of Dermatology 2008; 18: 185-187.
8. Kaminska-Winciorek G, Spiewak R. Dermoscopy on nevus comedonicus: a case report and review of the literature. Postępy Dermatologii i Alergologii 2013; 30: 252-254
9. Minagawa A. Dermoscopy-pathology relationship in seborrheic keratosis. Journal of Dermatology 2017; 44: 518- 524.
10. Kittler H, Rosendahl C, Cameron A, Tschandl P. 2011. Dermatoscopy: an algorithmic method based on pattern analysis. Austria: Facultas Verlags und Buchhandels AG, Universitatsverlag.
11. Niederkorn A, Ahlgrimm-Siess V, Fink-Puches R. Frequency, clinical and dermoscopic features of benign papillomatous melanocytic naevi (Unna type). British Journal of Dermatology 2009; 161: 510-514.
12. Goncharova Y, Attia EA, Souid K, Vasilenko IV. Dermoscopic features of facial pigmented skin lesions. ISRN Dermatology 2013; 2013: 546813.
13. Pizzichetta MA, Kittler H, Stanganelli I, Bono R, Cavicchini S et al. Pigmented nodular melanoma: the predictive value of dermoscopic features using multivariate analysis. British Journal of Dermatology 2015; 173: 106-114.
14. Ayhan E, Ucmak D, Akkurt Z. Vascular structures in dermoscopy. Anais Brasileiros de Dermatologia 2015; 90: 545- 53.