Clinical presentation of breast tuberculosis in eastern Anatolia

Breast tuberculosis is a very rare disease of the breast. This report aimed to review our clinical experience of 20 years and 7 cases of breast tuberculosis. Materials and methods: The records of 7 patients with breast tuberculosis were reviewed retrospectively. Results: The surgical procedure applied for breast tuberculosis comprised 1.3% of all surgical procedures of breast surgery. The mean age of the breast tuberculosis patients was 36 years, and all of the patients were female. The mean symptom duration was 12.8 months. The most common symptoms were painful breast mass in all the patients, 2 (28.6%) of whom had 8 cm or larger masses and sinus formation was observed in 5 (71.4%) patients. The diagnosis was confirmed by histopathological evaluation in all the patients. Five patients (71.4%) were treated with total excision of the breast mass, as well as the excision of sinus tracts, while abscess drainage with biopsy was applied in 2 patients (28.6%). All the patients were treated with triple or quadruple antituberculous drug regimens. Conclusion: Tuberculosis is a rare disease of the breast, and the breasts are a rare location for tuberculosis. The clinical presentation of breast tuberculosis patients in eastern Anatolia is different from the clinical presentation of such patients reported in the literature because their mean symptom duration is 1 year or over, all have a breast mass, which may be in very large sizes, and they present a sinus formation rate of 71.4%.
Anahtar Kelimeler:

Key words: Breast, tuberculosis

Clinical presentation of breast tuberculosis in eastern Anatolia

Breast tuberculosis is a very rare disease of the breast. This report aimed to review our clinical experience of 20 years and 7 cases of breast tuberculosis. Materials and methods: The records of 7 patients with breast tuberculosis were reviewed retrospectively. Results: The surgical procedure applied for breast tuberculosis comprised 1.3% of all surgical procedures of breast surgery. The mean age of the breast tuberculosis patients was 36 years, and all of the patients were female. The mean symptom duration was 12.8 months. The most common symptoms were painful breast mass in all the patients, 2 (28.6%) of whom had 8 cm or larger masses and sinus formation was observed in 5 (71.4%) patients. The diagnosis was confirmed by histopathological evaluation in all the patients. Five patients (71.4%) were treated with total excision of the breast mass, as well as the excision of sinus tracts, while abscess drainage with biopsy was applied in 2 patients (28.6%). All the patients were treated with triple or quadruple antituberculous drug regimens. Conclusion: Tuberculosis is a rare disease of the breast, and the breasts are a rare location for tuberculosis. The clinical presentation of breast tuberculosis patients in eastern Anatolia is different from the clinical presentation of such patients reported in the literature because their mean symptom duration is 1 year or over, all have a breast mass, which may be in very large sizes, and they present a sinus formation rate of 71.4%.

___

  • Tiwari VS, Agarwal A, Singh PK, Upadhyaya GC. Tuberculosis
  • of the breast. Ind J Tub 1990; 37: 149-51.
  • Tse GM. Granulomatous mastitis: a clinicopathological review of 26 cases. Pathology 2004; 36: 254-7.
  • Maroulis I, Spyropoulos C, Zolota V, Tzorakoleftherakis E. Mammary tuberculosis mimicking breast cancer: a case report. J Med Case Reports 2008; 2: 34.
  • Mankanjuola D, Murshid K, Al Sulaimani S, Al Salah M. Mammographic features of breast tuberculosis: the skin bulge and sinus tract sign. Clin Radiol 1996; 51: 354-8.
  • Das CJ, Kumar R, Balakrishnan VB, Chawla M, Malhotra A. Disseminated tuberculosis masquerading as metastatic breast carcinoma on PET-CT. Clin Nuclear Med 2008; 33: 359-61.
  • Schnarkowsky P, Schmidt D, Kessler M, Reiser MF. Tuberculosis of the breast: US, mammographic and CT findings. J Comput Assist Tomogr 1994; 18: 970-1.
  • Khurram M, Tariq M, Shahid P. Breast cancer with associated granulomatous axillary lymphadenitis: A diagnostic and clinical dilemma in regions with high prevelance of tuberculosis. Pathol Res Practic 2007; 203: 699-704.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Effect of L-carnitine on diabetic neuropathy and ventricular dispersion in patients with diabetes mellitus

Hızır ULVİ, Recep AYGÜL, Recep DEMİR

Exposure to continuous darkness leads to atypical symptoms of seasonal affective disorder in rats

Nimet Ünay GÜNDOĞAN, Ayhan Çağla İŞMAN, Neslihan TOYRAN

Isolation of Cryptococcus neoformans from pigeon droppings in Ahwaz, Iran

Majid ZARRIN, Masoomeh JORFI, Nasrin AMIRRAJAB, Morad ROSTAMI

Histopathologic changes in the rabbit submandibular gland after 5-fluorouracil chemotherapy

Fevzi Sefa DEREKÖY, Abdullah AYÇİÇEK, Oktay ÖZEL, Fethullah KENAR, Ramazan SARGIN, Fatma AKTEPE, Mustafa Deniz YILMAZ

Subclinical hypothyroidism in obese Turkish adolescents: the relationship with anthropometry and fatty liver

Ayhan ABACI, Benal BÜYÜKGEBİZ, Şamil HIZLI, Nur ARSLAN

Effects of adenosine A1 receptor agonist CCPA and antagonist DPCPX on ischemia/reperfusion-induced arrhythmias in rats*

Ömer BOZDOĞAN, Ersöz GONCA, Nuran EKERBİÇER

Effect of telmisartan on vascular endothelium in hypertensive and type 2 diabetic hypertensive patients

Burcu BARUTÇUOĞLU, Zuhal PARILDAR, Sara HABİF, Oya BAYINDIR, M. Işıl MUTAF, Emin ALİOĞLU, Dilek ÖZMEN

CD10 expression in urothelial bladder carcinomas: Staining patterns and relationship with pathologic parameters

Şükrü Oğuz ÖZDAMAR, Onak Nilüfer KANDEMİR, Nimet KARADAYI, Doğan Banu GÜN, Burak BAHADIR, Gamze YURDAKAN

Papiller tiroid karsinomlarında CK-19, cErb B2, galectin-3 ve p53 ekspresyonu

Nida SEÇKİN, Ülker KARAGECE

Anti-diabetic activity of Tinospora cordifolia (Willd.) in streptozotocin diabetic rats; does it act like sulfonylureas?

Nagaraja OURANIK, Kararashah Fakruddin KAMMAR, Seela DEVI