İdris AKKUŞ, Bünyamin KAPTANOĞLU, Ümran ÇALIŞKAN, Abdurrahman ÜNER, Mehmet GÜRBİLEK

Blood and fingernail copper (Cu) and magnesium (Mg) levels of chilldren with acute lymphoblastic leukemia

In this study, serum and fingernail Cu and Mg levels of 10 children with acute Iymphoblastic leukemia and 12 healthy children were determined. Copper and magnesium levels of the sera and supernatants were measured by atomic ab-sorption spectrophotometer. (Perkin-Elmer 400). Fingernail Cu and Mg levels of the patients were 8.67 ± 5.35 and 0.22 ± 0.12 $mu$mol/mg of nail respectively. The values for control subjects were 4.27 ± 2.32 and 0.14 ± 0.03 $mu$mol/mg of nail. Serum Cu and Mg levels of the patients were 525.1 ± 160.9 $mu$g/dl and 2.42 ± 0.54 mg/dl, and those of controls were 115.0 ± 70.7 $mu$g/dl and 2.20 ± 0.70 mg/dl respectively. The differences between serum Cu and fingernail Cu and Mg levels of the two groups were statistically significant which might be an index for the activity of the disease.

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