A comparison of the diagnostic value of 19-gauge histology and 22-gauge cytology needles in bronchoscopy for the evaluation of endobronchial lesions

To prospectively compare the sensitivity of Wang 22-gauge needle aspiration and 19-gauge needle aspiration with bronchial biopsy and determine whether there was difference between 22-gauge and 19-gauge needle aspirations in the diagnosis of endobronchial malignancies. Materials and methods: All patients (63 patients) in the study underwent fiberoptic bronchoscopy that included 22-gauge needle aspiration and 19-gauge needle aspiration. In 50 patients bronchial biopsy was done. The sensitivities of the individual techniques were compared. Results: Cancer was diagnosed in 48 patients by 22-gauge needle aspiration and 19-gauge needle aspiration, and in 43 patients by bronchial biopsy. The sensitivity of bronchial biopsy was 0.86. The addition of 22-gauge and 19-gauge needle aspirations to bronchial biopsy increased the sensitivity to 0.90 and 0.88, respectively, but the difference was not statistically significant (P = 1.0). The maximal diagnostic yield was obtained with the combination of needle aspirations and forceps biopsy in the detection of submucosal or peribronchial bronchogenic carcinoma (100%) (P < 0.05). Conclusion: The combination of forceps biopsy and transbronchial needle aspirations should be used for the highest rate of bronchoscopic diagnostic yield. However, there was no difference for increasing diagnostic yield in patients with visible endobronchial lesions between 22-gauge and 19- gauge needles.

A comparison of the diagnostic value of 19-gauge histology and 22-gauge cytology needles in bronchoscopy for the evaluation of endobronchial lesions

To prospectively compare the sensitivity of Wang 22-gauge needle aspiration and 19-gauge needle aspiration with bronchial biopsy and determine whether there was difference between 22-gauge and 19-gauge needle aspirations in the diagnosis of endobronchial malignancies. Materials and methods: All patients (63 patients) in the study underwent fiberoptic bronchoscopy that included 22-gauge needle aspiration and 19-gauge needle aspiration. In 50 patients bronchial biopsy was done. The sensitivities of the individual techniques were compared. Results: Cancer was diagnosed in 48 patients by 22-gauge needle aspiration and 19-gauge needle aspiration, and in 43 patients by bronchial biopsy. The sensitivity of bronchial biopsy was 0.86. The addition of 22-gauge and 19-gauge needle aspirations to bronchial biopsy increased the sensitivity to 0.90 and 0.88, respectively, but the difference was not statistically significant (P = 1.0). The maximal diagnostic yield was obtained with the combination of needle aspirations and forceps biopsy in the detection of submucosal or peribronchial bronchogenic carcinoma (100%) (P < 0.05). Conclusion: The combination of forceps biopsy and transbronchial needle aspirations should be used for the highest rate of bronchoscopic diagnostic yield. However, there was no difference for increasing diagnostic yield in patients with visible endobronchial lesions between 22-gauge and 19- gauge needles.

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Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Evaluation of the genotype MTBDRplus assay for the diagnosis of tuberculosis and rapid detection of rifampin and isoniazid resistance in clinical specimens

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Metabolic profi le and insulin resistance in patients with obstructive sleep apnea syndrome

Şahin ÖĞREDEN, Hale ARAL, Özgür YİĞİT, Güvenç GÜVENEN, Berrin BERÇİK İNAL, Mustafa ŞAHİN

A pooled analysis of the resistance patterns of Escherichia coli strains isolated from urine cultures in Turkey: a comparison of the periods 1997-2001 and 2002-2007

Meltem IŞIKGÖZ TAŞBAKAN, Sercan ULUSOY, Bilgin ARDA, Tansu YAMAZHAN, Hüsnü PULLUKÇU, Oğuz Reşat SİPAHİ

Th e causes of deaths in an industry-dense area: example of Dilovası (Kocaeli)

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Serum osteoprotegerin (OPG) measurement in Behçet's disease

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A comparison of two diff erent fl uorochrome stains for the detection of acid-fast bacilli in sputum specimens

Vildan AVKAN OĞUZ, Nurbanu SEZAK, Aygün ÖZTOP, Ayşe YÜCE, Süheyla SÜRÜCÜOĞLU, Nur YAPAR

Objective and subjective eff ects of surgical treatment of nasal obstructions in patients with asthma

Halil Erdem ÖZEL, Serpil ARIKAN, Özer Erdem GÜR, Cafer ÖZDEM

Serum osteoprotegerin (OPG) measurement in Behcet’s disease

Nesrin DEMİR, Nafiye Fulya İLHAN, Tamer DEMİR, Ahmet GÖDEKMERDAN

Potential role of some nutraceuticals in the regression of Alzheimer&#8217;s disease in an experimental animal model

Hanna Hamdy AHMED, Wafaa Ghoneim SHOUSHA, Rehab Mahmoud HUSSIEN, Abdel Razik Hussein FARRAG

The causes of deaths in an industry-dense area: example of Dilovası (Kocaeli)*

Onur HAMZAOĞLU, Nilay ETİLER, Cavit İşık YAVUZ, Çiğdem ÇAĞLAYAN