Sidelya Ecem YİĞİT, İffet Beril GÖKMEN, Yıldız OKUTURLAR

Ground Glass Appearance During the Pandemic Period: Everolimus Induced Interstitial Pneumonia

Ground glass appearance is a nonspecific finding that can see in diseases such as chronic interstitial disease, acute alveolar disease or infection; however, it is most commonly encountered in COVID-19 pulmonary involvement today. The mammalian target of rapamycin (mTOR) plays a regulatory role in cell proliferation and growth. Everolimus is an allosteric mTOR inhibitor used in ER+ breast cancers and inhibits the mTOR functional complex. Here, we present a case of interstitial pneumonia due to everolimus, which can be confused with COVID-19 pneumonia due to its ground-glass appearance during the pandemic period.

Keywords:

Everolimus, mTOR, ground glass interstitial pneumonia, Covid-19, breast cancer,

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