İlimizde helicobacter pylori sıklığının değerlendirmesi: yedi yıllık çalışma

Amaç: Helicobacter pylori’ (H.pylori) ye bağlı gelişen gastrit dünyada birçok ülkede yaygın olup insanda en sık görülen kronik enfeksiyonların başında gelmektedir. Dünya Sağlık Örgütü tarafından H. pylori’nin, mide karsinogenezisinin etyolojisinde temel rol aldığının bildirilmesiyle birlikte tüm dikkatler üzerine çevrilmiştir. Çalışmada ilimizdeki H.pylori pozitifliği sıklığı ve yıllar içindeki dağılımının belirlenmesi amaçlanmıştır. Gereç ve Yöntemler: 01.01.2013 ile 31.12.2019 tarihleri arasında Recep Tayyip Erdoğan Üniversitesi (RTEÜ) Eğitim ve Araştırma Hastanesi mikrobiyoloji laboratuvarına rutinde gelen gaita örneklerin kayıtlarının retrospektif olarak taranması şeklinde gerçekleştirilmiştir. Tüm klinik birimlerden gelen gaita örnekleri kabul edilmiş olup gelen numuneler kromatografik immünoassay bir test olan Rapid Cassette Test (Feces) (Acro, Biotech, Germany) kitleri ile hızlı antijen testleri üretici firmanın önerileri doğrultusunda çalışılmıştır. Bulgular: Toplam 8551 hastaya ait örnek çalışıldı. 806 tanesinin sonucu pozitif olarak sonuçlandı. Çalışılan örneklerin 5270’i (%61,6) kadın hastalara aitti. Bireylerin yaş ortalaması erkeklerde ±33.4 kadınlarda ±66.6 olup yaş ortalaması ±47.2 idi. Yıllar içindeki H. pylori pozitiflik sıklığı yaklaşık %1,2 -%21,2 arasında olup ortalaması %8,9 olarak bulundu. Sonuç: Çalışma sonucunda ilimizdeki H.pylori sıklığının ülke ortalamasının altında olduğunun görülmesine karşın yıllar içindeki sıklık artışı dikkat çekiciydi. Tanıda kullanılan hızlı antijen testi hızlı, güvenilir, basit olmasına karşın yanlış negatifliklere neden olabileceği de göz önünde bulundurulmalıdır.

Anahtar Kelimeler:

Helicobacter pylori, , hızlı antijen testi, sıklık

Evaluation of helicobacter pylori prevalance in our city: A seven years of study

Aim: Gastritis related to Helicobacter pylori (H.pylori) is common in many countries in the world and it is one of the most common chronic infections in humans. With the World Health Organization determining that H. pylori is involved in the etiology of gastric carcinogenesis, all attention has been turned on it. In this study, it was aimed to determine the frequency of H.pylori positivity in our province and its distribution over the years. Materials and Methods: The study was conducted between 01.01.2013 and 31.12.2019 in Recep Tayyip Erdogan University Training and Research Hospital microbiology laboratory. Stool samples from all clinical units were accepted and the samples were studied with Rapid Cassette Test (Feces) (Acro, Biotech, Germany) which are a chromatographic immunoassay test, in accordance with the manufacturer's recommendations. The study was conducted retrospectively. Results: A total of 8551 patient samples were studied. The results of 806 of them were positive. Of my studied samples, 5270 (61.6%) belonged to female patients. The mean age of the individuals was ±33.4 in males and ±66.6 in females and the mean age was ±47.18 years. The frequency of H. pylori positivity over the years was between 1.2% and 21.2%, with an average of 8.9%. Conclusion: Although the findings of the study showed that the frequency in our region was below the average of our country, the frequency increased over the years. Although the rapid antigen test used in diagnosis is fast, reliable and simple it should also be taken into consideration that it may cause false negativities.

Keywords:

Helicobacter pylori, rapid antigen test, prevalance,

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