Elif MENEKŞE, Muhammed EMİN DÜZ, Aydın BALCI, Mustafa DURMAZ

COVİD 19'DA ÖNE ÇIKAN BİYOKİMYASAL PARAMETRELERİN VE D VİTAMİNİNİN DEĞERLENDİRİLMESİ

Amaç: Bu çalışmada hastalığın seyrini tahmin etmek ve yoğun bakım ünitesine yatırılacak hastaları önceden belirlemek için potansiyel koagülasyon ve inflamasyon biyobelirteçlerini ve son dönemde sıkça vurgulanan D vitaminini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Bu retrospektif vaka-kontrol çalışması, Mart 2020'den Haziran 2020'ye kadar Amasya Sabuncuoğlu Şerefeddin Eğitim ve Araştırma Hastanesi'nde COVİD-19 tanısı alıp tedavi edilen 121 hasta üzerinde yapıldı. COVİD-19 ile ilişkili olabilecek D-dimer, fibrinojen, ferritin ve 25-OH Vitamin D'yi değerlendirdik. Hastalar, sadece polimeraz zincir reaksiyon pozitifliği (PCR +), sadece bilgisayarlı tomografi pozitifliği (CT +) ve hem PCR + hem de CT + olmak üzere üç gruba ayrıldı. Bulgular: Yaş ortalaması 53 olan 121 hasta incelendi (% 52 erkek). Sadece CT + hastalar diğer hastalardan daha yaşlıydı (p

Anahtar Kelimeler:

D-dimer, Ferritin, Fibrinojen, Vitamin D, COVİD 19, covid-19; d-dimer; ferritin; fibrinogen; vitamin d

EVALUATION OF FEATURED BIOCHEMICAL PARAMETERS AND VITAMIN D IN COVID-19

Aim: We aimed to evaluate potential coagulation and inflammatory biomarkers. The recently discussed vitamin D levels predict the course ef the disease and determine the patients to be admitted to the intensive care unit in advance. Materials and Methods: This retrospective case-control study was conducted on 121 patients diagnosed and treated with COVID-19 disease, from March 2020 to June 2020 at the Amasya Sabuncuoğlu Şerefeddin Training and Research Hospital, Amasya, Turkey. D-dimer, Fibrinogen, Ferritin, and 25-OH Vitamin D levels that could be associated with COVID-19 infections were evaluated. The patients were divided into three groups: only Polymerase Chain Reaction positivity (PCR+), only Computerized Tomography positivity (CT+) and both PCR+ and CT+ among COVID-19 cases. Results: 121 patients with at mean age of 53 were investigated (52% male). Only CT+ cases were significantly older than other patients, p

Keywords:

covid-19; d-dimer; ferritin; fibrinogen; vitamin d,

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