Synthesis of nitrogen-containing heterocycles from the reaction of amidrazones with $alpha$-haloesters

Synthesis of nitrogen-containing heterocycles from the reaction of amidrazones with $alpha$-haloesters

The reaction of amidrazones 1 with $alpha$-haloesters 2 formed 1,3,5-substituted 4,5-dihydro-l,2,4-triazin-6-ones (4a-z) rather than l,2,4-triazin-5-one derivatives (5a-z). The microanalysis and spectral data of the synthesized compounds are in full agreement with their molecular structure.

___

  • 1. R.M. Abdel-Rahman, Pak. J. Sci. Ind. Res. 30, 490 (1987).
  • 2. K.C. Joshi, A. Dandia and S. Khanna, Indian J. Chem. 26, 496 (1992).
  • 3. K.C. Joshi, R. Jain, A. Dandia and K. Sharma, Indian J. Chem. 28, 698 (1989).
  • 4. R.M. Abdel-Rahman, Pharmazine 56, 275 (2001).
  • 5. R.M. Abdel-Rahman and M.S. Abdel-Malik, Pak. J. Sci. Ind. Res. 33, 142 (1990).
  • 6. R.M. Abdel-Rahman, Pharmaco 46, 379 (1991).
  • 7. J. Wiley and H.U.S. Richard, U. S. 358590; Chem. Abstr. 98, 1072143 v (1983).
  • 8. B. Boehner, (Ciba-Geigy A.G.) Eur. Pat. (1986); Chem. Abstr. 105, 6522 e (1986).
  • 9. M.Z. Badr, M.M. Aly, Z.H. Khalil and A.A. Attalla, Indian J. Chem., Sect. B, 21, 115 (1982).
  • 10. G. Pitet, F. Court and Fr. Demande, FR 2500830; Chem. Abstr. 98, 72140 s (1983).
  • 11. Z. El-Gendy and R.M. Abdel-Rahman, Indian J. Heterocyclic Chem. 4, 293 (1995).
  • 12. Z. El-Gendy, J.M. Morsy, H.A. Allimony, W.R. Abdel-Monem and R. M. Abdel- Rahman, Pharmazine 56,376 (2001).
  • 13. R.M. Abdel-Rahman, M. Seada, M. Fawzy and M. El-Baz, Pharmazine 49, 729 (1994).
  • 14. A.S. Shawali, H.M. Hassaneen, A.A. Fahmi and N.M. Abu-Nada, Phosphorous, Sulfur and Silicon 53, 259 (1990).
  • 15. A.S. Ferwanah, A.M. Awadallah, E.A. El-Sawi and H.M. Dalloul, Synth. Com.mun. 33, 1245-1253 (2003).
  • 16. H.M. Dalloul and P.H. Boyle, Heterocycl. Commun. 9, 507 (2003).
  • 17. M.M. El-Abadelah, A.Q. Hussein and B.A. Thaher, Heterocycles, 32, 1879 (1991).
  • 18. A.M. Awadallah, A.S. Ferwanah, E.A. El-Sawi and H.M. Dalloul, Heterocycl. Commun. 8, 369 (2002).
Turkish Journal of Chemistry-Cover
  • ISSN: 1300-0527
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Chemoenzymatic Synthesis of 2-Bromo-6-Hydroxy-3-Methoxy-2-Cyclohexen-1-one

Emine Özgül KARAASLAN, Yasemin TOKA

Synthesis and Spectroscopic Characterization of New [Cu(tBusalpphen)]2, [MoCl2(salpphen)]2 Complexes and Sn2Cl8(tBusalpphen).2HNEt3 Adduct

Pelin SÖZEN, Yurdanur AKGÜL, Funda DEMİRHAN

Voltammetric and Spectroscopic Studies of Vanadium(V)-- Nicotinamide Interactions at Physiological pH

Semiha ÇAKIR, Ender BİÇER

Investigation of some 1-3-diols for the requirements of solvent extraction of boron: 2,2,6-trimethyl-1,3 heptanediol as a potential boron extractant

Servet TURAL, Bilsen TURAL, Halil HOŞGÖREN

On-Line Preconcentration and Speciation of Chromium by an 8-Hydroxyquinoline Microcolumn Immobilized on Surfactant-Coated Alumina and Flow Injection Atomic Absorption Spectrometry

Seyyed Hamid AHMADI, Ali Mohammad Haji SHABANI

Hydrothermal synthesis, characterization and photocatalytic activity of nanosized $TiO_2$ based catalysts for rhodamine B degradation

Murat ERDEMOĞLU, Meltem ASİLTÜRK, Sema ERDEMOĞLU, Hikmet SAYILKAN, Şadiye ŞENER, Funda SAYILKAN

Synthesis and Physico-chemical and Spectroscopic Investigations of Sodium Dihydrobis(1,2,3-benzotriazolyl)borate Ligand and Its Transition Metal Complexes

Ahmad UMAR, - LUTFULLAH, Mohammed Muzibur RAHMAN, Mohammad Mansoob KHAN, Yoon Bong HAHN

Voltammetric and spectroscopic studies of vanadium (V)-nicotinamide interactions at physiological pH

Ender BİÇER, Semiha ÇAKIR

Synthesis of nitrogen-containing heterocycles from the reaction of amidrazones with $alpha$-haloesters

Peter H. BOYLE, Hany M. DALLOUL

Synthesis and physico-chemical and spectroscopic investigations of sodium dihydrobis (1,2,3-benzotriazoly) borate ligand and its transition metal complexes

Mohammed Muzibur RAHMAN, Ahmad Umar LUTFULLAH, Mohammad Mansoob KHAN, Yoon Bong HAHN