M.Yakup ARICA, Vasıf HASIRCI, Mustafa LALE, N Fatma KÖK, Mustafa YİĞİTOĞLU

Controlled release of aldicarb from carboxymethylcellulese microcapsules

ISSN: 1300-0527
Yayın Aralığı: 6
Yayıncı: TÜBİTAK

Sodium carboxymethyl cellulose was converted into microspheres by crosslinking with aluminum chloride. Various microsheres with different amounts of crosslinker, biopolymer of various concentrations and molecular weights, and with different pesticide (Aldicarb) contents and pesticide to polymer ratios were prepared. The pesticide encapsulation efficiencies and aldicarb release kinetics of the resultant microcapsules were investigated. It was possible to modify the release behaviour by varying the above parameters and to have drug release with half-lives longer than 100 hours in aqueous media. The release kinetics were described by first order and zero order kinetics.

PDF

___

1. L. M. Benedetti, E. M. Topp, V. J. Stella, J. Controlled Release, 13, 33-41, 1990.
2. W. P. O'Neill, Membrane systems. Controlled Release Technologies: Methods, Theory and Applications, vol. I, Ed. A. F. Kydonieus, pp. 130-175, CRC Press, Boca Raton, FL, 1980.
3. R. Darvari and V. Hasirci, J. Microencapsulation, 13(1), 9-24, 1996.