Ömer DİLEK, Mustafa Ali TEZEREN, Tahir TİLKİ, Erkan ERTÜRK

Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes

Öz Starting from a chiral secondary alcohol, novel enantiopure 1,4-aminoalkylphenols (AAPs) were prepared by exploiting conventional organic transformations such as the Mitsunobu reaction, Eschweiler--Clarke N-methylation, and demethylation of anisoles. The catalytic activity of the 1,4-AAPs was investigated in enantioselective Et$_{2}$Zn addition to benzaldehyde. They were found to accelerate the Et$_{2}$Zn addition to benzaldehyde. High yields and enantioselectivities (e.g., 95% yield and 82% ee) were achieved.

Anahtar Kelimeler:

Asymmetric catalysis, aminoalcohols, aminoalkylphenols, diethylzinc addition

Tam Metin

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Bibtex	`@ { tbtkchem572829, journal = {Turkish Journal of Chemistry}, issn = {1300-0527}, eissn = {1303-6130}, address = {}, publisher = {TÜBİTAK}, year = {2019}, volume = {43}, pages = {612 - 623}, doi = {}, title = {Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes}, key = {cite}, author = {Dilek, Ömer and Tezeren, Mustafa Ali and Tilki, Tahir and Ertürk, Erkan} }`
APA	Dilek, Ö , Tezeren, M , Tilki, T , Ertürk, E . (2019). Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes . Turkish Journal of Chemistry , 43 (2) , 612-623 .
MLA	Dilek, Ö , Tezeren, M , Tilki, T , Ertürk, E . "Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes" . Turkish Journal of Chemistry 43 (2019 ): 612-623 <
Chicago	Dilek, Ö , Tezeren, M , Tilki, T , Ertürk, E . "Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes". Turkish Journal of Chemistry 43 (2019 ): 612-623
RIS	TY - JOUR T1 - Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes AU - Ömer Dilek , Mustafa Ali Tezeren , Tahir Tilki , Erkan Ertürk Y1 - 2019 PY - 2019 N1 - DO - T2 - Turkish Journal of Chemistry JF - Journal JO - JOR SP - 612 EP - 623 VL - 43 IS - 2 SN - 1300-0527-1303-6130 M3 - UR - Y2 - 2021 ER -
EndNote	%0 Turkish Journal of Chemistry Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes %A Ömer Dilek , Mustafa Ali Tezeren , Tahir Tilki , Erkan Ertürk %T Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes %D 2019 %J Turkish Journal of Chemistry %P 1300-0527-1303-6130 %V 43 %N 2 %R %U
ISNAD	Dilek, Ömer , Tezeren, Mustafa Ali , Tilki, Tahir , Ertürk, Erkan . "Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes". Turkish Journal of Chemistry 43 / 2 (Nisan 2019): 612-623 .
AMA	Dilek Ö , Tezeren M , Tilki T , Ertürk E . Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes. Turk J Chem. 2019; 43(2): 612-623.
Vancouver	Dilek Ö , Tezeren M , Tilki T , Ertürk E . Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes. Turkish Journal of Chemistry. 2019; 43(2): 612-623.
IEEE	Ö. Dilek , M. Tezeren , T. Tilki ve E. Ertürk , "Chiral 1,4-aminoalkylphenols for enantioselective diethylzinc addition to aldehydes", Turkish Journal of Chemistry, c. 43, sayı. 2, ss. 612-623, Nis. 2019