Ayse Banu DEMİR, Domenico BENVENUTO, Hakan ABACİOGLU, Silvia ANGELETTİ, Massimo CİCCOZZİ

9632

Identification of the nucleotide substitutions in 62 SARS-CoV-2 sequences from Turkey

A previously unknown coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been shown to cause coronavirus disease 2019 (COVID-19) pandemic. The first case of COVID-19 in Turkey has been declared in March 11th, 2020 and from there on, more than 150,000 people in the country have been diagnosed with the disease. In this study, 62 viral sequences from Turkey, which have been uploaded to GISAID database, were analyzed by means of their nucleotide substitutions in comparison to the reference SARS-CoV-2 genome from Wuhan. Our results indicate that the viral isolates from Turkey harbor some common mutations with the viral strains from Europe, Oceania, North America and Asia. When the mutations were evaluated, C3037T, C14408T and A23403G were found to be the most common nucleotide substitutions among the viral isolates in Turkey, which are mostly seen as linked mutations and are part of a haplotype observed high in Europe.
Keywords:

SARS-CoV-2, evolution, mutation, COVID-19,

PDF

___

  • Bai Y, 2020, EVOLUTION MOL CHARAC, DOI [10.1101/2020.04.24.058933, DOI 10.1101/2020.04.24.058933, 10.1101/2020.04.24.058933.]
  • Benvenuto D, 2020, J INFECTION, V81, pE24, DOI 10.1016/j.jinf.2020.03.058
  • Eden JS, 2020, VIRUS EVOL, V6, DOI 10.1093/ve/veaa027
  • Elbe S, 2017, GLOB CHALL, V1, P33, DOI 10.1002/gch2.1018
  • Eskier D., 2020, RDRP MUTATIONS ARE A, DOI [10.1101/2020.05.20.104885, DOI 10.1101/2020.05.20.104885]
  • Forster P, 2020, P NATL ACAD SCI USA, V117, P9241, DOI 10.1073/pnas.2004999117
  • Goh GKM, 2020, BIOMOLECULES, V10, DOI 10.3390/biom10020331
  • Gorbalenya AE, 2020, NAT MICROBIOL, V5, P536, DOI 10.1038/s41564-020-0695-z
  • Hillen HS, 2020, NATURE, V584, P154, DOI 10.1038/s41586-020-2368-8
  • Korber B., 2020, BIORXIV, DOI 10.1101/2020.04.29.069054
  • Li JG, 2020, J INFECTION, V81, P322, DOI 10.1016/j.jinf.2020.04.016
  • Lu J, 2020, CELL, V181, P997, DOI 10.1016/j.cell.2020.04.023
  • Ou XY, 2020, NAT COMMUN, V11, DOI 10.1038/s41467-020-15562-9
  • Pachetti M, 2020, J TRANSL MED, V18, DOI 10.1186/s12967-020-02344-6
  • Raj VS, 2013, NATURE, V495, P251, DOI 10.1038/nature12005
  • Rehman SU, 2020, PATHOGENS, V9, DOI [10.3390/pathogens9030240, 10.19045/bspab.2020.90001]
  • Shu YL, 2017, EUROSURVEILLANCE, V22, P2, DOI 10.2807/1560-7917.ES.2017.22.13.30494
  • van Dorp L., EVIDENCE INCREASED T, DOI [10.1101/2020.05.21.108506, DOI 10.1101/2020.05.21.108506]
  • Wang CT, 2020, J MED VIROL, V92, P667, DOI 10.1002/jmv.25762
Turkish Journal of Biology-Cover
  • ISSN: 1300-0152
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Arşiv
Sayıdaki Diğer Makaleler

Israt JAHAN, Ahmet ONAY

Cihan TASTAN, Bulut YURTSEVER, Gozde Sir KARAKUS, Derya Dilek KANCAGİ, Sevda DEMİR, Selen ABANUZ, Utku SEYİS, Mulazim YİLDİRİM, Recai KUZAY, Omer ELİBOL, Serap ARBAK, Merve Acikel ELMAS, Selcuk BİRDOGAN, Osman Ugur SEZERMAN, Aye Sesin KOCAGOZ, Koray YALCİN, Ercument OVALİ

Hamza Umut KARAKURT, Pinar PİR

Aftab ALAM, Mohd Faizan SİDDİQUİ, Nikhat IMAM, Rafat ALİ, Md MUSHTAQUE, Romana ISHRAT

Erman Salih ISTİFLİ, Arzuhan Sihoglu TEPE, Cengiz SARİKURKCU, Bektas TEPE

Ozlem BULUT, Ihsan GURSEL

Bertan Koray BALCİOGLU, Melis Denizci ONCU, Hasan Umit OZTURK, Fatima YUCEL, Filiz KAYA, Muge SERHATLİ, Hivda Ulbegi POLAT, Saban TEKİN, Aylin Ozdemir BAHADİR

Ayse Banu DEMİR, Domenico BENVENUTO, Hakan ABACİOGLU, Silvia ANGELETTİ, Massimo CİCCOZZİ

Osman Mutluhan UGUREL, Oguz ATA, Dilek TURGUT-BALİK

Tauseef AHMAD, Haroon HAROON, Kuldecip DHAMA, Khan SHARUN, Fazal Mehmood KHAN, Irfan AHMED, Ruchi TİWARİ, Taha Hussien MUSA, Muhammad KHAN, D. Katterine BONİLLA-ALDANA, Alfonso J. RODRİGUEZ-MORALES, Jin HUİ