Golden thistle belongs scolymus genus of Asteraceae family. Species which belongs to scolymus species are Scolymus maculatus L., Scolymus grandiflorus Desf. and Scolymus hispanicus L. in Turkey. Scolymus hispanicus L. is known as altın dikeni, sarıdiken, akkız, sarıcakız and akdiken. Golden thistle is consumed as food but also used as medicinal plants. Also it is one of rare plants which used as licensed drugs in Turkey. There is drugs which made from its root called “Lityazol Cemil” and it has been licensed. It was proofed that this drugs have effect on kidney stones, renal pelvis stones, ureter and bladder stones. There are golden thistle in almost everywhere in Turkey but it is only used at Aegean region especially at İzmir as vegetables. In this region, plant population were reduced because of intense gathering. In recent years, due to importance of this plant was increased and population of plants were reduces, study of cultivation of this plants were accelerated. Seed germination studies of this species have great importance in the determination of manufacturing strategy of production. In this study Scolymus hispanicus was conducted to determine the effects of various chemical applications (ethylene, gibberellin, mannitol, seaweed and cold pre-treatment). Experiment was established according to randomized design with 3 replications at Adnan Menderes University, Faculty of Agriculture, Field Crops Laboratory. Germination rate and germination power values have been determined that there are significant differences between applications