Arif ÇIMRIN, Öznur ABADOĞLU, Zeynep MISIRLIGİL, Levent AKYILDIZ, Tevfik ÖZLÜ, Aykut ÇİLLİ, Hasan BAYRAM

Real life profile of asthma and chronic obstructive pulmonary disease patients in Turkey

Giriş: Benzer semptomlar göstermelerine rağmen hava yollarının hastalıkları altta yatan farklı patofizyolojik olaylara sahiptir ve uygun tedavinin uygulanabilmesi için ayırt edilmeleri gerekir. Astım/kronik akciğer hastalığı (KOAH) hastalarındaki tedaviye uyum zayıflığının klinisyen ve hasta ile ilişkili nedenleri çok sayıda çalışmada değerlendirilmiştir. Bu çalışmada, Türkiye'deki yeni tanı almış tedavisiz astım ve KOAH hastalarının klinik ve sosyodemografik özelliklerini belirlemek amaçlanmıştır. Materyal ve Metod: Bu ulusal, çok merkezli, gözlemsel çalışma 122 merkezde yürütülmüştür. Demografik, klinik, laboratuvar parametreleri ile ilişkili kriterleri içeren bir anket kullanılmıştır. Tüm hastaların 12 ay süreyle izlenmesi planlanmıştır. Bulgular: Çalışmaya122 merkezden 1892 erişkin hasta (1116 astım ve 776 KOAH) alınmıştır. İntermitan, hafif persistan ve orta persistan astım hastalarının sırasıyla %95, %86 ve %65'i aşırı tedavi görmektedir. KOAH hastaları arasında, aşırı tedavi görenlerin yüzdeleri GOLD evre A, B ve C için sırasıyla %66, %79 ve %82'dir. Tedaviye uyumu yüksek hastalar arasında tam kontrol altındaki hasta oranı astım hastalarında %44, GOLD evre A KOAH hastalarında %41'dir. Art arda iki vizitte, bu oran astım hastalarında %52 ve %63'e, KOAH hastalarında %54 ve %50'ye artma göstermiştir. Sonuç: Başlıca sonuçlar; astım ve KOAH'lı hastalar (a) sıklıkla aşırı tedavi almaktadır ve (b) tahmin edilebileceği gibi vizitlere uyum göstermemektedir

Türkiye’de astım ve kronik obstrüktif akciğer hastalığı olan hastalarda gerçek yaşam profili

Introduction: Despite the presentation of similar symptoms, the airway diseases have different underlying pathophysiological processes and must be distinguished to enable the administration of appropriate treatment. In several studies the clinician- and patient-related causes of poor compliance to treatment in asthma/chronic obstructive pulmonary disease (COPD) patients have been evaluated. This study aimed to determine the clinical and sociodemographic characteristics of newly diagnosed treatment-naïve asthma and COPD patients in Turkey.Materials and Methods: This national, multicentre, prospective, observational study was conducted in 122 centres. A questionnaire including items related to demographic, clinical, laboratory parameters was applied. All patients were intended to be followed-up for 12 months. Results: 1892 adult patients (1116 asthma and 776 COPD) from 122 centres were enrolled. Overall 95%, 86% and 65% of intermittent, mild persistent and moderate persistent asthma patients were over-treated. Among COPD patients, the percentages of over-treated patients were 66%, 79% and 82% for those with GOLD stage A, B and C. Physicians’ adherence to guidelines was appropriate in 93% of severe persistent asthma patients and 89% of GOLD stage D COPD patients. Among patients with high compliance to treatment, proportion of asthma patients with total control was 44% and that of COPD patients at GOLD stage A was 41%. In consecutive two visits, this figure increased to 52% and 63% in asthma patients and 54% and 50% in COPD patients.conclusion: The main findings are: (a) patients are frequently over-treated and (b) patients do not adhere to visits as expected, in both asthma and COPD

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