Nuray KÖMÜS, Hülya ELLİDOKUZ, Arif Hikmet ÇIMRIN, Can SEVİNÇ, Kemal Can TERTEMİZ

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Kronik obstrüktif akciğer hastalığında mortalite ve mortaliteyi etkileyen faktörler

Giriş: Kronik obstrüktif akciğer hastalığı (KOAH) dünyadaki önde gelen mortalite ve morbidite nedenlerinden birisidir.Araştırmalarda mortalite oranlarının %15-54 arasında değiştiği görülmektedir. Ülkemizde KOAHta mortalite ve mortalitey-le ilişkili faktörleri değerlendiren sınırlı sayıda çalışma bulunmaktadır. Araştırmamızın amacı kliniğimizde izlenen KOAHlıhastalarda, mortalite oranını saptamak ve mortaliteyi etkileyen faktörleri araştırmaktır.Hastalar ve Metod: Temmuz 2004-Kasım 2005 tarihleri arasında saptanan KOAHlı 427 olgu değerlendirildi.Bulgular: Ortalama dört yıllık süre sonunda mortalite oranı %17.3 olarak bulundu. Ölümler en sık pulmoner, ikinci sıklık-ta ise kardiyak nedenlere bağlıydı. Akciğer kanserine bağlı ölümler %31 oranında idi. Yaş, sigara içme miktarı, KOAH ev-resi, FEV1 (L), FEV1 % beklenen, FVC (L), FVC% beklenen, FEV1/FVC, PEF (L/saniye), PEF % beklenen, FEF25-75 (L) ve FEF25-75% beklenen değerler, komorbid hastalık varlığı, Modifiye Borg Skalası ve MMRCye göre dispne şiddeti, altı dakika yürü-me mesafesi ve test sonrası oksijen satürasyonu, BODE indeksi, SF-36 yaşam kalitesi anketinin fiziksel fonksiyon, fizikselrol, emosyonel rol ve enerji skorları alt parametreleriyle SGRQ anketinin tüm parametrelerinin mortalite ile istatistiksel ola-rak anlamlı düzeyde ilişkili olduğu görüldü.Sonuç: KOAH, mortalitesi yüksek bir hastalıktır ve önemli toplum sağlığı problemlerinden birisini oluşturmaktadır. KOAHizleminde spirometrik ölçümler yanında egzersiz kapasitesi ve yaşam kalitesi gibi diğer ölçütlerin kullanılması teşvik edil-melidir. Hastalar ve risk grubundaki olguların bilinçlendirilmesi, risk faktörlerinin önlenebilir oluşu nedeniyle önemlidir. Buyöntem komorbid hastalıkların önlenmesine de katkıda bulunabilir.

Mortality and factors affecting mortality in chronic obstructive pulmonary disease

Introduction: Chronic obstructive pulmonary disease (COPD) is one of the major causes of mortality and morbidity in theworld. Mortality rates vary between 15-54% in investigations. There is a limited number of studies evaluating factors asso-ciated with mortality and morbidity in our country. The aim of this study is to detect the mortality rate and to investigatethe factors affecting mortality.Patients and Methods: 427 patients with COPD between July 2004-November 2005 were evaluated.Results: Mortality rate was found to be 17.3% at the end of four years. Deaths were most frequently due to pulmonary ca-uses and secondly cardiac factors. Deaths due to lung cancer were 31%. Age, amount of smoking, COPD stage, FEV1 (L),FEV1% predicted, FVC (L), FVC% predicted, FEV1 /FVC, PEF (L/sn), PEF% predicted, FEF25-75 (L) and FEF25-75% predicted va-lues, presence of comorbid diseases, Modified Borg Scale and dyspnea severity according to MMRC, six minutes walkingtest and oxygen saturation following the test, BODE index, SF-36 quality of life questionnaire, physical function, physicalrole, emotional role and energy scores parameters and all parameters of SGRQ questionnaire were found to be significantlyassociated with mortality.Conclusion: COPD is a disease with high mortality and is one of the problems related with the public health. In the followup of COPD, the usage of other measures like exercise capacity and quality of life besides spirometric measures should beencouraged. To make the patients and cases in the risky group conscious of their disease is important since the risk factorsare preventable. This method may also contribute to the prevention of comorbid diseases.
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Tüberküloz ve Toraks-Cover
  • ISSN: 0494-1373
  • Yayın Aralığı: 4
  • Başlangıç: 1951
  • Yayıncı: Tuba Yıldırım
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