In order to agricultural health, many species of plants can be used on controlling insects and keeping of the stored foods safely. One of these plants is Azadirachta indica. It has an effect on nutrition, ovulation prevention and doing toxic effect for numerous pests. Therefore, it can be used for fighting agricultural pests. On the other hand, Tribolium castaneum is known to damage to the stored products and dry foods. Because of having short life cycle and ability of leaving a lot of eggs of a female, it is one of the important pest.It was aimed to find the effect of variable seed powder of A. indica on T. castaneum reproduction in this study. Three different mediums were prepared for reproduction of T. castaneum insects in the study. None of the seed powder of A. indica plant was used in the first medium. However, in the other two mediums, the seed powder of A. indica was used for 10% and 40% ratios respectively. After three weeks the larvae which were in the mediums were counted. According to obtained results 211 larvae were in the medium where the seed powder of A. indica wasn’t applied in, 127 larvae were in the medium where the seed powder of A. indica was 10% and 100 larvae were in the medium where the seed powder of A. indica was 40% respectively. These results showed the effect of variable quantities seed powder of A. indica on T. castaneum reproduction.