Zeynep Banu Doğanlar, Derya Demirbağ Kabayel, Hande Özdemir, Filiz Tuna

Is there a difference in 25-hydroxyvitamin D levels between female university students with and without joint hypermobility?

Objectives: Individuals with joint hypermobility (JH) constitute a sensitive group with regard tomusculoskeletal problems. This study aimed to investigate whether females with generalized jointhypermobility (GJH) are at risk of hypovitaminosis D compared with non-GJH female participants and whetherthere is a relationship between vitamin D levels, Beighton score and musculoskeletal complaints.Methods: In this cross-sectional, descriptive and case-control study, 76 female participants aged 18-25 yearswere included. The Beighton score with a cut-off of 4/9 was applied for defining GJH. In addition, serumbiochemical (the enzymatic colorimetric method) and hormonal (the electrochemiluminescence method)parameters were evaluated.Results: The mean serum 25-hydroxyvitamin D (25[OH]D) levels of GJH (n = 38) and non-GJH (n = 38)groups were 15.70 ± 7.96 ng/mL and 16.80 ± 5.45 ng/mL, respectively. There was no statistically significantdifference between the groups in terms of biochemical and hormonal parameters. We found vitamin Ddeficiency in 89.5% of participants with GJH, and 84.2% of controls. There was no correlation between vitaminD, Brighton criteria, and musculoskeletal complaints.Conclusion: The female participants with GJH showed similar frequency of musculoskeletal complaints andsimilar low level of 25(OH)D in relation to controls.

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