Ufuk AKER, SERPİL MİŞE YONAR

Banyo yoluyla oksitetrasiklin uygulanan pullu sazan (Cyprinus carpio)’ da paraoksonaz ve arilesteraz enzim aktivitelerindeki değişimlerin araştırılması

: Bu çalışmada, pullu sazan (Cyprinus carpio)‘a farklı konsantrasyonlarda uygulanan oksitetrasiklinin paraoksonaz (PON) ve arilesteraz (ARE) enzim aktivitelerine etkisinin ortaya çıkarılması amaçlandı. Bu amaçla oksitetrasiklin 50 ve 75 mg/L konsantrasyonlarında 48 saat süreyle banyo tarzında balıklara uygulandı. Oksitetrasiklin uygulamasından sonraki 7., 14. ve 21. günlerde kontrol ve deneme grubunda balıklardan karaciğer ve serum örnekleri alındı. Alınan örneklerde PON ve ARE enzim aktivitelerindeki değişimler belirlendi. Oksitetrasiklin uygulanan grupların karaciğer ve serumundaki PON ve ARE enzim aktiviteleri kontrol grubuna kıyasla azaldı. Bu azalma 7., 14. ve 21. günlerde kontrol grubundan istatistiksel olarak farklı bulundu. Anahtar kelimeler: Arilesteraz, Cyprinus carpio, enzim, oksitetrasiklin, paraoksonaz Abstract: In this study, it was aimed to reveal the effects on paraoxonase (PON) and arylesterase (ARE) enzyme activities of oxytetracycline applied in different concentrations in scaly carp (Cyprinus carpio). For this purpose, oxytetracycline at doses of 50 and 75 mg/L was applied by bathing for 48 hours. On the 7th, 14th and 21st days after the application of oxytetracycline, liver and serum samples were taken from the fish in the control and experimental groups. Changes in the PON and ARE enzyme activities were determined in the liver and serum samples which collected from the fish. The PON and ARE activities in the liver and serum decreased in the groups exposed to oxytetracycline compared to that of the control group. This reduction was statistically different from the control group on 7, 14 and 21 days.

Investigation of changes in paraoxonase and arylesterase enzyme activities in scaly carp (Cyprinus carpio) applied oxytetracycline by bath

In this study, it was aimed to reveal the effects on paraoxonase (PON) and arylesterase (ARE) enzyme activities of oxytetracycline applied in different concentrations in scaly carp (Cyprinus carpio). For this purpose, oxytetracycline at doses of 50 and 75 mg/L was applied by bathing for 48 hours. On the 7th, 14th and 21st days after the application of oxytetracycline, liver and serum samples were taken from the fish in the control and experimental groups. Changes in the PON and ARE enzyme activities were determined in the liver and serum samples which collected from the fish. The PON and ARE activities in the liver and serum decreased in the groups exposed to oxytetracycline compared to that of the control group. This reduction was statistically different from the control group on 7, 14 and 21 days.

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